过敏性疾病儿童皮肤点刺试验反应性评价:一项横断面研究

K. Kumar, Rsv Srikrishna, I. Pavan, M. Surendranath, M. Nagaraju
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引用次数: 0

摘要

过敏性疾病是通过暴露于环境物质和遗传易感性之间的复杂相互作用而发展起来的。在过去十年中,全球过敏性疾病的患病率有所增加。本横断面研究旨在评价皮肤点刺试验在儿童变应性疾病中的反应性。总共招募了400名年龄在1-12岁之间的儿童。采用14种标准化过敏原提取物在前臂掌面进行皮肤点刺试验(SPT)。以哮喘(52.5%)居多,其次为特应性皮炎(22.75%)和变应性鼻炎(15.75%)。饮食习惯引发过敏的儿童占76%,环境因素占4.75%,宠物占8.25%,室内条件占11%。皮肤点刺试验对鸡蛋(13.5%)、牛奶(22%)、小麦(9.75%)、苹果(4.5%)、谷物(6.5%)、猫(18%)、狗(6%)、小蠊(9.5%)、烟曲霉(9.5%)、真菌(12.75%)、farina皮癣菌(24.75%)、pteromyssinus皮癣菌(23.75%)、Blomia tropicalis(9.5%)和Bermuda grass(13.75%)呈阳性。确定儿童特应性疾病过敏原致敏模式对选择正确的预防和治疗策略至关重要,有助于提高儿童的生活质量。
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Evaluation of skin prick test reactivity in children with allergic diseases: A cross sectional study
Allergic diseases are developed through complex interaction between exposure to environmental substances and genetic susceptibility. The prevalence of allergic diseases has increased during last decade globally. The present cross sectional study was designed to evaluate the skin prick test reactivity in children with allergic diseases. A total of 400 children between age group 1-12 years were recruited. The Skin prick tests (SPT) using 14 standardized allergen extracts were conducted in the volar surface of forearm. Majority children had asthma (52.5%), followed by atopic dermatitis (22.75%) and allergic rhinitis (15.75%). Food habits triggering allergic conditions in 76% children, environmental factors in 4.75% children, pets in 8.25% and indoor conditions in 11% children. Skin prick test was positive to egg (13.5%), milk (22%), wheat (9.75%), apple (4.5%), cereals (6.5%), cat (18%), dog (6%), blatella (9.5%), aspergillus fumigatus (9.5%), fungi (12.75%), Dermatophytes farina (24.75%), Dermatophytes pteromyssinus (23.75%), Blomia tropicalis (9.5%) and Bermuda grass (13.75%). Determination of allergen sensitization patterns in children with atopic disease is crucial for selecting proper preventive and therapeutic strategies which helps to improve quality of life of in children.
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