根据2014年Bethesda系统的巴氏涂片细胞学谱

Kamna Gupta, Preety Garg, A. Mohan, Rajnish Kumar, A. Varshney
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摘要

宫颈癌是全世界妇女死亡的主要原因之一。巴氏涂片是一种有价值的筛查宫颈肿瘤病变的工具。本研究旨在对宫颈病变进行临床细胞学相关性分析,了解研究人群宫颈病变谱。在Muzaffarnagar医学院病理学系进行了一项观察性研究。共纳入1,017名女性,取宫颈刮片,采用Papanicolaou染色法处理。这些染色的涂片在显微镜下检查,并根据最新的Bethesda系统2014进行分类。在1017例病例中,84.9%(863例)的涂片根据2014年Bethesda系统分类为满意。31 ~ 40岁年龄组占多数(350例,40.5%)。在340名女性中,NILM是最常见的细胞学发现(39.3%)。上皮异常包括非典型鳞状细胞(ASCUS, ASC-H),鳞状上皮内病变(LSIL, HSIL)和鳞状细胞癌,占总数的3.2%。LSIL占1.3%,HSIL占1.0%。单例SCC检出。宫颈上皮异常在印度女性中很常见。巴氏涂片是最方便和OPD检测上皮异常的早期阶段。应鼓励对巴氏涂片筛查的认识,以减少宫颈癌引起的发病率和死亡率。
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Spectrum of Pap smear cytology according to The Bethesda System 2014
Carcinoma of cervix is one of the leading cause of mortality in women across the world. Papanicolaou smear is a valuable screening tool for the neoplastic lesions of cervix. Present study was carried out to do clinicocytological correlation of cervical lesions and to find out the spectrum of cervical lesions in study population. An observational study was conducted at Pathology department in Muzaffarnagar Medical College, Muzaffarnagar. Total 1,017 females were enrolled, scrape smears from the cervix were taken and processed using Papanicolaou's method of staining. These stained smears were examined under microscope and classified according to latest The Bethesda System 2014. Out of 1017 cases, 84.9% (863) smears were classified satisfactory according to 2014 The Bethesda System. Majority of cases (350 cases, 40.5%) belonged to age group of 31-40 years. NILM was the most common cytological finding seen in 340 females (39.3%). The epithelial abnormalities including Atypical Squamous Cells (ASCUS, ASC-H), Squamous Intraepithelial Lesion (LSIL, HSIL) and Squamous Cell Carcinoma were seen in 3.2% of total cases. LSIL found in 1.3% cases and HSIL formed 1.0%. Single case of SCC was detected. Cervical epithelial abnormalities are common in Indian females. Pap smear is the most convenient and OPD test to detect epithelial abnormalities in early phase. Awareness regarding the Pap screening should be encouraged to lessen the morbidity and mortality caused by Carcinoma Cervix.
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