赤藓提取物的生物活性测定及其在医学生物技术中的应用

I. Iancu, L. Bucur, V. Schroder, M. Apetroaei
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摘要

“如今,我们看到人们对植物疗法的兴趣越来越大,对副作用更小的草药产品也越来越感兴趣。近年来,有一种药用植物的受欢迎程度显著下降,它是罗马尼亚传统医学中已知的对胃肠道疾病有益的植物。本研究采用BSLA(盐水对虾致死试验)评价水曲(Lythrum salicaria L.)花尖三种不同提取液(水提液、醇提液、丙酮提液)的生物活性,并采用扩散法测定提取液对两种医学上重要的参比菌株(金黄色葡萄球菌和大肠杆菌)的抑菌活性。我们证明了这样一个事实,即Lythri herba植物产品提取物(水、醇和丙酮)缺乏急性毒性,以及对革兰氏阳性参考菌株金黄色葡萄球菌的适度抗菌作用,从而强调了将该植物用于生物医学应用的可能性。”
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TESTING THE BIOLOGICAL ACTIVITY OF LYTHRI HERBA EXTRACT FOR APPLICATIONS IN MEDICAL BIOTECHNOLOGIES
"Nowadays we are witnessing an increased interest in phytotherapy and implicitly for herbal products that have lower side effects. One medicinal plant whose popularity has decreased significantly in recent years is Lythrum salicaria L., loosestrife, known in Romanian traditional medicine for its beneficial effects against gastrointestinal diseases. The aim of this study is to evaluate the biological activity of three different extracts (aqueous, alcoholic, acetonic) from the flower tips of Lythrum salicaria L. using the BSLA (Brine Shrimp Lethality Assay) test and the antimicrobial activity of the extracts on two reference bacterial strains which are important for the medical field (Staphylococcus aureus and Escherichia coli) through the diffusimetric method. We demonstrated the fact that the Lythri herba plant product extracts (aqueous, alcoholic, and acetonic) lack acute toxicity, as well as the moderate antibacterial effect on the Gram-positive reference strain, Staphylococcus aureus, thus highlighting the possibility of using the plant in biomedical applications."
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