子宫颈癌筛查的回顾性研究-在印度东部新开设的三级保健中心

R. Saha, Deepika Pandey, S. Mondal, T. Santosh, Sujaya Mazumder, I. Chakrabarti
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摘要

宫颈癌是最常见的癌症之一,也是不发达国家妇女死亡的主要原因。巴氏涂片检查是发现感染和癌前病变的一项基本检查。本研究旨在了解宫颈筛查在发现癌前病变、恶性病变和非肿瘤病变方面的作用,以及接受传统巴氏涂片技术的妇女中不同病变的患病率。我们筛选了在Kalyani AIIMS产科和妇科门诊就诊的15-70岁年龄组的妇女。所有同意接受巴氏涂片检查的妇女都包括在内。2133例中绝大多数为良性,其中上皮内病变阴性或恶性(NILM)约1989例(93.24%),炎性705例(33.05%)。非典型鳞状细胞44例(2.06%),不典型鳞状细胞不能排除HSIL 3例(0.14%),低级别鳞状上皮内病变(LSIL) 11例(0.52%),高级别鳞状上皮内病变(HSIL) 5例(0.23%),非典型腺细胞7例(0.33%)。202例无症状女性(9.47%)中,上皮细胞异常12例(0.56%)(ASCUS 8例,LSIL 2例,ASCH 1例,hsil 1例)(优势比=0.5056,显著性水平,P=0.0362)。传统的巴氏涂片检查是一种非常简单和廉价的诊断工具,可以检测癌前、恶性和非肿瘤病变以及各种病变的患病率。根据美国癌症协会(ACS)的规定,子宫颈抹片检查应从25岁开始,直到65岁(每3年重复一次)。
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A retrospective study on cervical cancer screening- In a newly opened tertiary care Centre in Eastern India
: One of the most prevalent cancers, cervical cancer is also the leading cause of mortality for women in underdeveloped nations. A fundamental test for finding infections and precancerous diseases is the Papanicolaou smear. This study aims to comprehend the function of cervical screening in detecting premalignant, malignant, and non-neoplastic lesions as well as the prevalence of different lesions in women who received a traditional pap smear technique. We screened women in the age group of 15-70 years who attended the Outpatient department of the Obstetrics and Gynaecology department of AIIMS, Kalyani. All women who gave consent for screening by Pap smear test were included. Of 2133 cases, most of the cases were benign comprising of Negative for Intraepithelial Lesion or malignancy (NILM) of about 1989 (93.24%) cases, 705 (33.05%) inflammatory. Atypical squamous cells of undetermined significance in 44 cases (2.06%), Atypical squamous cells cannot exclude HSIL in 3 (0.14%), low-grade squamous intraepithelial lesion (LSIL) in 11 (0.52%), high-grade squamous intraepithelial lesion (HSIL) in 5 (0.23%) women and Atypical glandular cell in 7 (0.33%). Out of 202 asymptomatic women (9.47%), 12 cases (0.56%) showed epithelial cell abnormality (8 ASCUS, 2 LSIL, 1 ASCH, 1HSIL) (Odds ratio=0.5056, Significance level, P=0.0362). Conventional Pap smear test is a very easy and cheap diagnostic tool to detect premalignant, malignant, and non-neoplastic lesions and the prevalence of various lesions.  As per the American Cancer Society (ACS), a pap smear should start from 25 years to be done till 65 years (repeated after every 3 years).
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