{"title":"DNA/RNA数据处理的三种生物信息学管道的比较","authors":"Jiang Lijun, Wenxian Yang, Rongshan Yu, Shiqian Wu, Anisha Anil Lekshmy","doi":"10.1109/ICIEA.2017.8282818","DOIUrl":null,"url":null,"abstract":"Most of the genetic instructions like growth, development, functioning, reproduction of all human beings are carried out by DNA molecule. The DNA and RNA are both nucleic acids, which contains proteins, carbohydrates, and one of three major types of macromolecule that are essential for all forms of life. In this project, we take the samples of the DNA and do testing and data processing with it. During the process for alignment and variant calling for DNA, we use three types of aligners and three variant callers. The aligners are BWA, BOWTIE, and SNAP. The variant callers are SAMtools.","PeriodicalId":443463,"journal":{"name":"2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA)","volume":"285 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of three bioinformatics pipelines for DNA/RNA data processing\",\"authors\":\"Jiang Lijun, Wenxian Yang, Rongshan Yu, Shiqian Wu, Anisha Anil Lekshmy\",\"doi\":\"10.1109/ICIEA.2017.8282818\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Most of the genetic instructions like growth, development, functioning, reproduction of all human beings are carried out by DNA molecule. The DNA and RNA are both nucleic acids, which contains proteins, carbohydrates, and one of three major types of macromolecule that are essential for all forms of life. In this project, we take the samples of the DNA and do testing and data processing with it. During the process for alignment and variant calling for DNA, we use three types of aligners and three variant callers. The aligners are BWA, BOWTIE, and SNAP. The variant callers are SAMtools.\",\"PeriodicalId\":443463,\"journal\":{\"name\":\"2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA)\",\"volume\":\"285 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICIEA.2017.8282818\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2017 12th IEEE Conference on Industrial Electronics and Applications (ICIEA)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICIEA.2017.8282818","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of three bioinformatics pipelines for DNA/RNA data processing
Most of the genetic instructions like growth, development, functioning, reproduction of all human beings are carried out by DNA molecule. The DNA and RNA are both nucleic acids, which contains proteins, carbohydrates, and one of three major types of macromolecule that are essential for all forms of life. In this project, we take the samples of the DNA and do testing and data processing with it. During the process for alignment and variant calling for DNA, we use three types of aligners and three variant callers. The aligners are BWA, BOWTIE, and SNAP. The variant callers are SAMtools.
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