基于磁镊和全内反射荧光显微镜的细胞力学研究微操作平台

The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004. Pub Date : 2004-12-15 DOI:10.1109/APBP.2004.1412350

Chaug-Chun Lee, Cheng-hao Chien, Liang-Kung Wen, C. Dong

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摘要

我们开发了一个操作平台，结合磁镊子和孵育系统，全内反射荧光显微镜(TIRFM)。我们的系统可以产生高达nN范围的力，这些力可以用来观察和表征细胞对外力的机械反应。结合TIRFM，还可以研究细胞表面应力-应变现象。

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A micromanipulation platform based on magnetic tweezers and total internal reflection fluorescence microscopy for cell mechanical studies

We developed a manipulation platform, which combines magnetic tweezers and the incubating system, with total internal reflection fluorescence microscopy (TIRFM). Our system can generate forces up to the nN range and such forces can be used to observe and characterize cell mechanical responses to external forces. Combined with TIRFM, cell surface stress-strain phenomena can also be investigated.

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The Second Asian and Pacific Rim Symposium on Biophotonics, 2004. APBP 2004.

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