硅基介孔生物活性玻璃的性质和治疗潜力

M. Ikram, S. Hussain, M. Javed
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引用次数: 0

摘要

生物活性材料由于其在各个领域的惊人性能,近年来受到了人们的广泛关注。生物活性玻璃(BGs)被用作生物医学应用的一部分,如抗菌材料。可采用溶解灭火法或溶胶-凝胶技术来释放BGs。2000年首次报道了杀菌剂掺杂银溶胶-凝胶推断的介孔硅基生物活性玻璃,合成了76SiO2-19CaO-2P2O5-3Ag2O (wt%),平均孔径为28 nm。掺入银、铜、锌、铈和镓等金属元素的生物活性玻璃是本次审计的重点,其中SiO2、SiO2- cao和SiO2- cao - p2o5框架被纳入母玻璃创作。普通用途的掺有抗菌颗粒的介孔BGs包括骨组织修复,用于骨科器械和眶内植入的多功能陶器涂层,具有升级血管生成潜力的支架,骨刺激和抗菌特性,用于治疗各种骨缺陷和伤口恢复。
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Nature and Therapeutic Potential of Silica-based Mesoporous Bioactive Glass
Bioactive materials have received much consideration in the last couple of years because of their astounding properties in various fields. Bioactive Glasses (BGs) are utilized as part of biomedical applications, such as antibacterial materials. BGs can be delivered by means of dissolve extinguishing strategy or sol-gel technique. Bactericidal silver-doped sol-gel inferred mesoporous silica-based bioactive glasses were accounted for the first time in 2000, having the synthesis 76SiO2-19CaO-2P2O5-3Ag2O (wt%) and a mean pore width of 28 nm. Bioactive glasses doped with metallic elements such as silver, copper, zinc, cerium and gallium are the focus of this audit in which SiO2, SiO2-CaO and SiO2-CaO-P2O5 frameworks are incorporated as the parent glass creations. Run of the mill uses of mesoporous BGs doped with antibacterial particles incorporate bone tissue recovery, multifunctional earthenware coatings for orthopedic gadgets and orbital inserts, scaffolds with upgraded angiogenesis potential, osteostimulation and antibacterial properties for the treatment of various bone imperfections and also in wound recuperating.
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