T. H. Hong, S. Choi, Jeong soo Kim, Kee-Hwan Kim, H. Seo, J. Kim, C. Ahn, W. Park, S. Oh, S. Jung, K. W. Lim
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引用次数: 0
摘要
。分期、组织学分级、雌激素受体(ER)和孕激素受体(PR)。结果:结果显示，IGF-IR、IRS-1表达与ER、PR呈正相关，与组织学分级呈反比关系。IGR-IR和IRS-1与患者的年龄和临床分期没有关联。在生存分析中，IGF-IR和IRS-1的表达与无病生存率没有明确的相关性。结论:IGF-IR和IRS-1似乎在乳腺癌的进展和分化中发挥作用，与ER和PR有关(Journal of Korean breast cancer Society 2003;6:283-290)。
The Clinical Application of Insulin-like Growth Factor-I Receptor (IGF-IR) and Insulin Receptor Substrate-1 (IRS-1) Expression in Breast Cancer
인슐린유사성장인자(Insulin-like Growth Factor (IGF))이다. stage, the histological grade, the estrogen receptor (ER) and the progesterone receptor (PR). Results: The results showed that IGF-IR and IRS-1 expression positively correlated with the ER and PR, and an inverse relationship was found between the IGF-IR and IRS-1 and histological grades. No association was observed between the IGR-IR and IRS-1 and the patent's age and clinical stage. In survival analysis, there was no definite association between the expressions of IGF-IR and IRS-1 and the disease free survival rate. Conclusion: IGF-IR and IRS-1 appear to play a role in the progression and differentiation of breast cancer in association with the ER and the PR. (Journal of Korean Breast Cancer Society 2003;6:283-290)
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