{"title":"实现超过百万倍的荧光增强生物传感应用","authors":"L. Velmanickam, I. T. Lima, D. Nawarathna","doi":"10.1109/RAPID49481.2020.9195707","DOIUrl":null,"url":null,"abstract":"We have demonstrated that AC electric fields can be used to amplify the intensity of fluorophore molecules. AC electric fields enhance the metal-fluorophore-light interactions, which produce significant enhancements of fluorescence intensities. This concept can be applied to developing sensitive biosensors for clinical applications.","PeriodicalId":220244,"journal":{"name":"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)","volume":"61 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Achieving over million-fold fluorescence enhancement for biosensing applications\",\"authors\":\"L. Velmanickam, I. T. Lima, D. Nawarathna\",\"doi\":\"10.1109/RAPID49481.2020.9195707\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We have demonstrated that AC electric fields can be used to amplify the intensity of fluorophore molecules. AC electric fields enhance the metal-fluorophore-light interactions, which produce significant enhancements of fluorescence intensities. This concept can be applied to developing sensitive biosensors for clinical applications.\",\"PeriodicalId\":220244,\"journal\":{\"name\":\"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)\",\"volume\":\"61 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/RAPID49481.2020.9195707\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2020 IEEE Research and Applications of Photonics in Defense Conference (RAPID)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/RAPID49481.2020.9195707","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Achieving over million-fold fluorescence enhancement for biosensing applications
We have demonstrated that AC electric fields can be used to amplify the intensity of fluorophore molecules. AC electric fields enhance the metal-fluorophore-light interactions, which produce significant enhancements of fluorescence intensities. This concept can be applied to developing sensitive biosensors for clinical applications.
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