尘肺病与非粉尘暴露工人慢性阻塞性气道疾病的比较

W T Ulmer
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引用次数: 0

摘要

许多种类的灰尘,包括香烟的烟雾,会导致肺功能受损。只要粉尘不是纤维性的,这种肺功能损伤不会影响工作能力。石英通常存在于煤矿粉尘中,浓度在2%至10%之间,一些作者声称它是煤矿工人尘肺病(CWP)的原因。然而,证据是相互矛盾的,目前还不能得出确切的结论。从临床角度来看,CWP的特点是气道阻力增加。CWP合并阻塞性气道疾病患者的气道阻力、动脉氧和二氧化碳压力以及胸内气体体积(IGV)之间的所有相关性与非粉尘暴露的阻塞性气道疾病患者相似。在气道阻力相等的情况下,CWP患者的IGV平均值较小。CWP合并阻塞性气道疾病患者的动脉氧压和肺动脉压的关系与慢性阻塞性气道疾病但无CWP的患者相同。CWP合并阻塞性气道疾病的治疗效果与没有CWP的患者非常吻合。
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Chronic obstructive airway disease in pneumoconiosis in comparison to chronic obstructive airway disease in non-dust exposed workers.

Many types of dust, including cigarette smoke, cause an impairment of lung function. This lung function impairment does not affect working capacity provided the dust is not fibrogenetic. Quartz, normally present in coal mine dust in concentrations between 2 and 10% is claimed to be responsible for coal workers' pneumoconiosis (CWP) by some writers. However the evidence is conflicting and firm conclusions cannot be drawn at present. From the clinical point of view CWP is characterized by an increased airway resistance. All correlations between airway resistance, arterial oxygen and carbon dioxide pressure and intrathoracic gas volumes (IGV) in patients having CWP and obstructive airway disease are similar to those in non-dust exposed patients with obstructive ariway disease. Patients with CWP, at equivalent values of airway resistance have smaller mean values of IGV. The relationship between arterial oxygen pressure and pulmonary arterial pressure is the same in patients with CWP and obstructive airway disease as in patients with chronic obstructive airway disease but without CWP. The effect of therapy in CWP with obstructive airway disease corresponds very well to that seen in patients without CWP.

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Proteolytic Mechanisms and Pulmonary Emphysema [A method of continuous recording on microsamples of the Hb-O2 association curve. II. A study of Bohr effect and carbamino-formation (author's transl)]. A method of continuous recording on microsamples of the Hb-O2 association curve. I. Technique and direct registration of standard results. [Relationships of seric IgA and s.IgA of bronchial secretions with respiratory pathophysiology (author's transl)]. Respiratory impairment including assessment of disability. Budapest, Hungary, June 22-26, 1975. 1. Summary of the conference.
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