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引用次数: 0

摘要

合成生物学有“两个灵魂”,一个专注于为现有生命设计新的特征,另一个旨在创造新的生命。就长期的科学和哲学影响而言,创造生命的目标可以说要重要得多。“创造生命”考虑的是自下而上创造生命的方法,从简单的化学物质开始,只从现有的生物中获取灵感。到目前为止,自我复制的催化循环已经产生,从简单的前体产生中等复杂的分子。那些致力于密封的人已经制造出了自我复制的膜泡,尽管这些膜泡需要一些复杂的起始分子。似乎尚未完成的是将这些概念结合起来。
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7. Creating life
Synthetic biology has ‘two souls’, one focused on engineering new features into existing life, the other aiming to create life de novo. The goal of creating life is arguably far more significant in terms of long-term scientific and philosophical impact. ‘Creating life’ considers the approach to creating life from the bottom up, starting with simple chemicals and taking only inspirations from existing living things. So far, self-reproducing catalytic cycles have been generated that produce molecules of modest complexity from simple precursors. Those working on containment have made self-reproducing membrane vesicles, albeit ones requiring somewhat complex starting molecules. What seems not yet to have been done is to join these concepts.
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8. Cultural impact 5. Synthetic biology for engineering 1. Biology: from analysis to synthesis 4. Synthetic biology and healthcare 6. Synthetic biology for basic research
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