用金黄色葡萄球菌从城市污水中获得的噬菌体的特性

Anderson Luis Pena da Costa, Antonio Carlos Freitas Souza, R. Resque
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引用次数: 2

摘要

噬菌体是一种细菌病毒,由于其作为抗生素替代品的潜力,以及它们在选择性控制对食物有害的细菌种类方面的适用性,在过去的几十年里受到了极大的关注。在此背景下,本工作报道了一种名为P4CSa的病毒滤液的部分结果,该滤液由金黄色葡萄球菌获得,并通过病毒宿主范围和限制性片段长度多态性技术进行了表征。结果表明,噬菌体P4CSa可能属于Caudovirales目,具有多价宿主范围,并可在4℃条件下以滤过的裂解物形式长期保存,提示该噬菌体P4CSa可能具有开发生物防治致病菌药物的潜力。微生物学报,Vol.10 (1) 2020: 20-24
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Characterization of a bacteriophage from urban sewage obtained with the bacterium Staphylococcus aureus
Bacteriophages are viruses of bacteria that have received significant attention in the last decades due to their potential as an alternative to the antibiotics, as well as their applicability in the selective control of bacterial species harmful to food. In this context, this work reports the partial results of a viral filtrate named P4CSa that was obtained with the bacterium Staphylococcus aureusand characterized by the viral host range and the restriction fragment length polymorphism technique. The results indicate that the phage P4CSa probably belongs to the order Caudovirales, it presents a polyvalent host range, and it can be preserved for the long term in the form of filtrated lysates stored at 4°C, suggesting that the phage P4CSa may have the potential for the development of a pharmaceutical product indicated for the biocontrol of pathogenic bacteria. Stamford Journal of Microbiology, Vol.10 (1) 2020: 20-24
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