Hajar医院心脏病和CCU住院患者急性心脏病发作与LDL-C血清水平的关系:对一个悖论的回答

M. Lotfizadeh, A. Khaledifar, Foroogh Heidari, Abdolvahab Khdemi
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摘要

背景和目的:急性心肌梗死(MI)是世界上最常见的心脏病之一,包括在伊朗。本研究的目的是探讨急性心肌梗死与急性心肌梗死患者血清低密度脂蛋白(LDL)水平之间的关系。方法:采用人口普查方法,选择在Shahrekord Hajar医院住院的1274例心肌梗死患者。根据纳入标准从患者的医疗记录中提取所需信息。统计学分析采用方差分析(ANOVA)和卡方检验检验LDL水平与患者意识的关系。结果:本组急性心脏病发作患者平均年龄为13.79±63.18岁。在1274名被研究的患者中,78%(999人)是男性,其余是女性。在男性和女性中,大多数患者的LDL水平在70至129 mg/dL之间。关于他汀类药物的使用,分别有757、287和162人有他汀类药物使用史、高血压史和心血管疾病史。此外,分别有150人和152人患有糖尿病和有吸烟史。本研究发现,LDL组他汀类药物使用史(P<0.0001)与心肌梗死频率(P=0.049)之间存在显著关系。结论:这项研究的结果揭示了低密度脂蛋白组与急性心脏病发作次数之间的显著关系,急性心脏病发作是一个长期并发症。
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The relationship between acute cardiac attack and LDL-C serum levels in cardiac and CCU inpatients in Hajar hospital: Replying to a paradox
Background and aims: Acute myocardial infarction (MI) is one of the most prevalent heart diseases across the world, including in Iran. The purpose of the present study was to investigate the relationship between acute MI and serum low-density lipoprotein (LDL) levels in patients with acute MI. Methods: In this descriptive-inferential study, 1274 MI patients hospitalized in Shahrekord Hajar Hospital were selected using the census method. The required information was drawn from the patient’s medical records according to inclusion criteria. Statistical analyses were performed using analysis of variance (ANOVA) and chi-square test to examine the relationship between the LDL level and awareness in patients. Results: In this study, the average age of patients with acute heart attack was 13.79±63.18 years. Of the 1274 studied patients, 78% (999 people) were men and the rest were women. In both male and female genders, most patients had LDL levels between 70 and 129 mg/dL. Regarding statin use, 757, 287, and 162 people had a history of statin use, hypertension (HTN), and cardiovascular disease, respectively. In addition, 150 and 152 people had diabetes and a history of smoking, respectively. In this study, a significant relationship was found between the history of statin use (P<0.0001) and the frequency of MI (P=0.049) in LDL groups. Conclusion: The results of this research revealed a significant relationship between LDL groups and the number of times acute heart attack occurs as a long-term complication in people who have had one.
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