益生菌在鼻腔过敏中的作用研究

Prashanth Veerabhadraiah
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引用次数: 0

摘要

摘要:乳酸菌是人类肠道中常用的益生菌之一,是一种主要的共生菌群。它具有超越基本营养的健康益处,其在增加宿主免疫调节能力方面的作用已被广泛接受。在治疗过敏性疾病方面,益生菌的有益作用已得到证实。目的观察益生菌对鼻过敏症状的缓解作用。方法对50例变应性鼻炎(AR)患者给予益生菌治疗,为期6周,对患者症状(流鼻、打喷嚏、鼻塞)的VAS评分和IgE评分进行统计分析。收集治疗前后的VAS评分和IgE评分并进行分析。结果结果显示,服用益生菌后,得分有所下降。结论:本前瞻性研究表明,在急性鼻炎患者中,给予益生菌可显著改善鼻出血、打喷嚏和鼻塞的vas和IgE评分。关键词:变应性鼻炎、益生菌、鼻塞、鼻出血和打喷嚏
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A STUDY ON THE ROLE OF PROBIOTICS IN NASAL ALLERGY
INTRODUCTION: One of the major components of the commensal microbial flora, which is being frequently used as probiotics in the intestinal tract of humans, is Lactobacilli. It exerts health benefits beyond inherent basic nutrition, and its role in increasing the immunomodulating capacity of the host is widely accepted. In the treatment of allergic diseases, the beneficial effect of probiotics has been demonstrated. OBJECTIVE This study was aimed to observe the effectiveness of probiotics in reducing the symptoms of nasal allergy. METHODS Total 50 patients suffering from Allergic Rhinitis (AR) were administered with probiotics for a period of six weeks post which the VAS and IgE scores of the symptoms (Rhinorrhea, Sneezing, and Nasal obstruction) were statistically analyzed. The pre and post treatment VAS and IgE scores were collected and analyzed. RESULTS It showed that there was a reduction in the scores after the administration of probiotics. CONCLUSIONS This prospective study demonstrated the presence of significant improvement in the VAS and IgE scores among the following nasal symptoms - Rhinorrhea, Sneezing, and Nasal obstruction with the administration of probiotics in the patients suffering with AR. KEYWORDS Allergic rhinitis, probiotics, nasal obstruction, rhinorrhea and sneezing.
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