[使用市售的纤维连接蛋白检测试剂盒检测胎膜破裂]。

W A Reus, C Hofstaetter, A Mährlein, J W Dudenhausen
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引用次数: 0

摘要

在一项临床检查中,试图证实商业上可用的免疫测定法检测羊水的能力。使用羊膜穿刺术获得的纯羊水,不与其他分泌物混合。在使用三个不同批次的检测中,该试验的灵敏度总计为35/55,即64%。我们得出的结论是,目前的测试是不够可靠的证明或反驳羊水的排放。特别需要解释的是,在宫缩过程中发生的力所起的作用,以及当发现胎儿纤维连接蛋白存在时,宫颈和阴道分泌物的存在。胎儿纤维连接蛋白的证据可能会成为更重要的预测即将分娩的证据,而不是证明羊水混合在宫颈和阴道分泌物中。
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[Detection of rupture of fetal membranes using a commercially available fibronectin test kit].

In a clinical examination an attempt was made to confirm the aptitude of a commercially available immunoassay to detect amniotic fluid. Pure amniotic fluid gained by amniocentesis, not mixed with other secretions, was used. On examination using three different batches the sensitivity of this test amounted to 35/55 in all, or 64%. We came to the conclusion that the present test was not sufficiently reliable to prove or disprove the discharge of amniotic fluid. An explanation is needed especially regarding the role played by the forces which occur during contractions and the presence of cervical and vaginal secretions when fetal fibronectin is found to be present. The evidence of fetal fibronectin could possibly become more important as a predictor of imminent labour than as being proof of the admixture of amniotic fluid in cervical and vaginal secretions.

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[Symposium on Uterine Contraction and Beginning of Labor. Aachen, September 1993]. [Uterine contraction and labor onset. Overview]. [Control of labor onset in the human]. [Biochemical principles of cervix ripening and dilatation]. [Role of the cervix uteri at labor onset from ultrasound studies].
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