浅谈药物遗传学

Siniša Franjić
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引用次数: 0

摘要

药物遗传学研究基因决定的对药物反应的变异。药物遗传学研究导致对药物治疗的不同反应的DNA序列的个体间差异。药物遗传学的最终目标是在个性化医疗的原则上建立治疗方法,在这种原则下,每个人,即病人,都被当作一个个体来对待。实现这一目标的方法是使用分子诊断方法来确定患者的药理学状态,并提供根据患者需要调整治疗的可能性。
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A Few Words about Pharmacogenetics
Pharmacogenetics deals with genetically determined variations in response to drugs. Pharmacogenetics studies interindividual differences in DNA sequence that lead to a variable response to drug therapy. The ultimate goal of pharmacogenetics is to establish treatment on the principles of the personalized medicine in which each person, ie patient, is approached as an individual. The way to achieve this is to use molecular diagnostic methods to determine the pharmacogenetic status of the patient and to provide the possibility of adjusting the treatment to his needs.
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