快速和可控的弹性毛细管流动通道使用悬浮膜

S. Fishlock, David Steele, S. Puttaswamy, G. Lubarsky, César Navarro, William P. Burns, J. McLaughlin
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引用次数: 1

摘要

在微流控纸基分析设备(μPADS)中控制流体速度和流速的能力将有助于实现更敏感和灵活的护理点(POC)诊断。我们提出了一种弹性毛细管通道设计,用于多孔膜中的流体流动,与标准、非悬浮格式的多孔膜相比,它可以将流速增加4.45倍。随着通道宽度的变化,流量的增加是可控的,并通过使用弹性毛细管作用来实现,其中柔性多孔膜悬浮在刚性基板上,并在流体吸胀过程中变形。这种技术在POC诊断中特别有用,因为需要在最小体积损失的情况下快速运输和混合小样本。
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Fast and controllable elastocapillary flow channels using suspended membranes
The ability to control the fluid velocity and flow rate in microfluidic paper-based analytical devices (μPADS) will help to enable more sensitive and flexible point-of-care (POC) diagnostics. We present an elastocapillary channel design, for fluid flow in porous membranes, which enables an increase in flow velocity by a factor of up to 4.45 compared with a porous membrane used in a standard, non-suspended, format. The increase in flow rate is controllable with varying channel width, and is enabled by using an elastocapillary action, where the flexible porous membrane is suspended over a rigid substrate and deformed during fluid imbibition. This enabling technology is particularly useful in POC diagnostics, where small samples need be rapidly transported and mixed with minimal loss of volume.
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