形态发生蛋白结合异种移植物用于萎缩性上颌重建术1例

Gustavo Henrique Romani Magalhães, N. S. Rocha, F. Araújo, Bruno de Macedo Santana, F. Landim, A. Figueiredo Filho
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引用次数: 0

摘要

颌骨萎缩后,由于牙体的缺失和骨的吸收,颌骨萎缩后的康复成为了一个挑战。自体、异种和同种异体移植物以及同种异体生物材料等替代材料已被用于骨体积增加。将上颌窦提升到上颌后区域的技术在文献中有很好的描述,并且没有出现主要的并发症。形态发生蛋白(BMPs)在该技术中作为佐剂出现,可以替代移植物或与移植物结合。本研究的目的是介绍使用不同的材料来重建萎缩的上颌骨,以恢复患者失去的骨轮廓和体积。报告的病例显示重组人骨形态发生蛋白2 (rhBMP-2)的使用,与颗粒异种移植物相关。对萎缩的上颌骨进行了重建,并讨论了该技术的适应症、禁忌症和可能的局限性。可以得出这样的结论:所使用的技术是令人满意的;该患者进展良好,正在等待植入式假肢的安装。
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Use of morphogenetic protein associated with xenogeneic graft for atrophic maxilla reconstruction: case report
With the loss of dental elements and subsequent bone resorption, the rehabilitation process in an atrophic maxilla becomes a challenge for professionals. Alternatives such as autogenous, xenogeneic and allogeneic grafts, as well as alloplastic biomaterials, have been used for bone volume gain. The technique of lifting the maxillary sinus to the posterior region of the maxilla is well described in the literature and does not present major complications. Morphogenetic proteins (BMPs) appear as adjuvants in this technique and can replace grafts or be combined with them. The objective of this study was to present the use of different materials for the reconstruction of the atrophic maxilla in order to give back to a patient the bone contour and volume she had lost. The reported case shows the employment of recombinant human bone morphogenetic protein 2 (rhBMP-2), associated with a particulate xenogeneic graft. The atrophic maxilla was reconstructed, and the indications, contraindications and possible limitations of the technique were discussed. It is possible to conclude that the technique used was satisfactory; the patient evolved well and is awaiting installation of an implant-supported prosthesis.
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