基于单向换能器驱动的倾斜驻面声波运动模式的粒子声阻抗分离

Cheng Chen, Yuting Wang, Keyu An, Zhongyuan Ren
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摘要

声阻抗分离技术因其生物相容性好、无接触、无标签、高效等优点而受到广泛关注。本文提出了一种基于运动模式的基于单向换能器驱动的倾斜驻面声波(TaSSAW)分离粒子的方法。实验结果表明,所设计的电极宽度可控单向换能器能有效提高声波利用率,增加声辐射力。结果表明,当颗粒密度和压缩率接近流体密度和压缩率,颗粒形状接近球形时,流体粘度和颗粒形状对声辐射力的影响可以忽略不计。研究发现,在TaSSAW系统中,粒子的运动模式可分为锁定模式和漂移模式,它们与流体速度、声场强度和标题角有关。基于运动模式的不同,对半径为4 μm和5 μm的聚苯乙烯(PS)颗粒进行了分离。对于尺寸差更小的颗粒(4.5 μm和5μm),通过使颗粒以相同的漂移方式运动,也成功地实现了分离。所提出的TaSSAW体系在生物化学领域具有广阔的应用前景。
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Acoustophoresis Separation of Particles Based on Motion Modes via Tilted-Angle Standing Surface Acoustic Wave Driven by a Unidirectional Transducer
Acoustophoresis separation technique has attracted great attention due to its superior properties, such as biocompatibility, non-contact, label-free and high-efficiency. In this paper, separation of particles based on motion modes via tilted-angle standing surface acoustic wave (TaSSAW) driven by a unidirectional transducer is developed. It’s verified that the designed electrode width controlled unidirectional transducers are effective to improve the acoustic wave utilization rate and increase the acoustic radiation force. The results show that when the density and compressibility of the particles are close to those of the fluid and the particle shape is close to spherical, the influences of fluid viscosity and particle shape on the acoustic radiation force are negligible. It’s found that in the TaSSAW system the motion modes of the particles are divided into locked mode and drift mode, and they depend on the fluid velocity, acoustic field intensity and title angle. polystyrene (PS) particles with radii of 4 and 5 μm are separated based on the differences of motion modes. For further smaller size difference (4.5 and 5μm) particles, the separation is also realized successfully by making particles move in the same drift mode. The proposed TaSSAW system has broad application prospects in biology and chemistry.
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