应用于生物芯片的金属微丝传感器的制造与表征

V. Perumal, N. Amil, N. Aiman, U. Hashim
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引用次数: 3

摘要

微丝尺寸小,灵敏度高,是一种很好的传感器。为了发挥作用,微电极传感器必须与能够处理这些信号的电子设备集成在一起。在本研究中,我们展示了一种用于生物传感应用的金属微丝器件的制造和表征方法。利用传统的光刻技术和其他实验技术,我们开发了一种生产具有微米尺度特征的铝线的可靠方法。值得注意的是,在微加工中,光刻晶圆的临界尺寸(CD)是决定器件最终性能的最重要参数。因此,高分辨率、高灵敏度和精确对准是将原始图案成功转移到晶圆上的关键。通过控制光刻胶(PR)涂层的旋转速度、旋转时间、曝光后烘烤时间、显影剂浓度比、硬烘烤和铝蚀刻时间对工艺进行优化,以达到可能的制备工艺和预期的微细线尺寸。该工艺从光抗胶涂层开始,并以3000转/分的速度旋转,形成一层薄而均匀的层。随后,将PR涂层的基材暴露在紫外光下10s。对准曝光后,用25份显影剂和10份去离子水的25:10比例的抗蚀剂显影剂显影。最后,对曝光后烘烤时间和硬烘烤时间进行了优化,以提高图案传递过程的吞吐量。铝制微丝已成功地与接触垫制成。导线的厚度范围为1 μm-4μm,以达到尽可能低的电阻率,以达到纳米范围的检测极限。这种微电极传感器最终将被用作生物分子检测试剂盒。利用原子力显微镜(AFM)、扫描电镜(SEM)、高倍显微镜(HPM)对制备的微丝进行了形貌表征。此外,利用源计对制备的铝微线的电学性能进行了研究。
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Fabrication and characterization of metal microwire transducer for biochip application
Microwire makes good sensors because their small dimensions which enhance their sensitivity. To be useful, microelectrode sensors must be integrated with electronic capable of processing those signal. In this research, we demonstrated a method to fabricated and characterize metal microwire device for biosensing application. Using conventional photolithography technique and other experimental techniques, we developed a reliable procedure for producing aluminium wires with micron-scale features. Significantly, in micro fabrication the critical dimension (CD) of wafers in photolithography is the most important parameter that determines the final performance of devices. Hence, it is paramount to have high resolution, high sensitivity and precise alignment to successfully transfer the original pattern to wafer. The process was optimized by control the spin speed for photoresist (PR) coating, spin time, post exposure bake time, developer concentration ratio, hard bake and aluminium etch time so as to achieve the possible fabrication process and get the expected microwire size. The process begins with the photoresists coating and spinning at 3000 rpm to form a thin and uniform layer. Subsequently, the PR coated substrates were exposed to UV light for 10s. After the alignment and exposure, the substrate were developed using the resists developer with 25:10 ratio in which 25 parts of developer and 10 parts of deionized water. Eventually, the post exposure bake and hard bake time were optimized for a better throughput on the pattern transfer process. The aluminium microwire has been successfully fabricated with the contact pads. The wires range in thickness from 1 μm-4μm to achieve a resistivity as low as possible for nano range limit of detection. This microelectrodes transducer will be eventually used as biomolecule detection kit. The fabricated microwire was morphologically characterized using Atomic force microscope (AFM), Scanning electron microscope (SEM), High power microscope (HPM). Besides that, the electrical properties of the fabricated aluminium microwire were studied using source meter.
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