基于DSC-MRI的大脑热传递率映射

Werawat Chewpanyanun, M. Matsumae, T. Horie, Kuroda Kagayaki
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引用次数: 0

摘要

组织的热传递率(HTR)是在激光治疗下控制脑组织温度的一个主要问题。对于计划,根据研究(7),计划设置脑组织的HTR,通过与钆(Gd)磁共振成像(DSC-MRI)对比,应用动态敏感性的组织残留曲线提供脑血流量(CBF)的结果。该研究通过研究两个HTR图中的胶质母细胞瘤和脑膜瘤组织样本,绘制了脑组织CBF在每个温度水平下的传热图。本研究对5例样本患者采用多病变灌注弥漫性增强(n = 1)、不规则性增强(n = 1)和环状增强(n = 3),并将样本CBF的灌注率与数据库进行比较。脑组织温度为34℃~ 43℃时HTR值与肿瘤分析结果一致;肿瘤边缘的HTR值升高,而肿瘤内部的HTR值较低。另一个结果是肿瘤内部的HTR高,而边缘的HTR低。HTR数据可用于生物传热方程下的组织模拟。
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Heat Transfer Rates Mapping in The Brain based on DSC-MRI
The Heat Transfer Rate (HTR) of tissue is a major problem in controlling the brain tissue temperature under laser therapy to remove a tumor. For the planning, Planning, according to research (7), to set HTR of the brain tissue provides the result of the cerebral blood flow (CBF) by applying the tissue residue curves of dynamic susceptibility in contrast to magnetic resonance imaging (DSC-MRI) with gadolinium (Gd). The research created a map of heat transfer for every temperature level for brain tissue CBF by studying the samples of Glioblastoma and Meningioma tissues in the two HTR diagrams. This research, studied five sample patients by using perfusion of multiple lesions diffuse enhancement (n = 1), irregular enhancement (n = 1), and ring enhancement( n = 3). The perfusion rate from CBF of the samples was compared with the database. The result, of the HTR value HTR, at a brain tissue temperature of 34°C to 43 °C had the same result as from the analysis of the tumor; HTR increases around the rim of the tumor while the value inside is low. Another result was the HTR inside the tumor was high, while the HTR at the rim was low. The HTR data could be used to simulate tissue under the equation of bio-heat transfer.
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