多普勒雷达呼吸测量在门控肺癌放疗中的应用

Changzhan Gu, Ruijiang Li, Changzhi Li, Steve B. Jiang
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引用次数: 27

摘要

呼吸门控放射治疗是一种很有前途的治疗方式,它可以精确地向肺肿瘤提供规定的辐射剂量,同时最大限度地减少正常组织并发症的发生率和严重程度。传统的门控技术要么依赖于植入的基准标记物,要么依赖于外部替代物,比如放置在患者腹部的标记物。它们要么是侵入性的,要么没有足够的准确性。本文提出了一种非接触式多普勒雷达无创测量呼吸信号的方法,由此可以得到精确的门控信号来控制直线机。我们的方法不需要标记,使用起来非常方便。我们使用5.8 GHz正交雷达测量呼吸作用。对测量信号进行了分析。研究表明,非接触式呼吸测量方法能够为移动肿瘤的放射治疗提供可靠的呼吸运动和准确的门控信号。
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Doppler radar respiration measurement for gated lung cancer radiotherapy
Respiration-gated radiation therapy is a promising treatment modality that precisely delivers prescribed radiation dose to the lung tumor while minimizing the incidence and severity of normal tissue complications. Conventional gating techniques either rely on implanted fiducial markers or external surrogates such as markers placed on patients' abdomen. They are either invasive to the patients or do not have sufficient accuracy. In this paper, we present a non-contact Doppler radar method to non-invasively measure the respiration signals, from which, accurate gating signals can be derived to control the linac. No marker is needed in our method, which makes it very convenient in use. We measured the respiration using a 5.8 GHz quadrature radar. Analysis of the measured signal is presented. It has been shown that the non-contact means of respiration measurement is able to supply reliable breathing motions and accurate gating signals for radiotherapy of mobile tumors.
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