测定粉末流动特性的技术

Shaveta Sharma, Teenu Sharma, Mahak Deep, Ashima Sharma
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引用次数: 1

摘要

当前工作的目标是使用药典和非药典程序对粉末和颗粒的流动进行有序的评估。评估休止角、密度、卡尔压缩系数、体积密度、豪斯纳比。此外,利用粉末流变仪描述了流量,其中精密的力传感器筛选由于样品位移而产生的力,这是另一种技术FT4粉末流变仪。弗里曼技术(FT4粉末流变仪)旨在描述粉末在不同情况下的方式,看起来像大规模的创造气候。技术包括安全性和不规则流速、可压缩性、剪切细胞、空气循环、孔隙度、隔板接触和结合。FT4已在包括药品、精细合成物质、化妆品、食品、添加剂和粉末覆盖在内的整个粉末制备企业中得到了应用。FT4的应用涉及灌装、料斗流量、片剂压力、湿造粒、终点、流量添加物的测定和增强、水分影响、静态变化、进料、搅拌、分离、结块、加工、壁栅、握把、料斗配置等。
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Techniques to Determine Powder Flow Properties
The goal of the current work was to do an orderly assessment of flow of powders and granules using compendial and non-compendial procedure. Angle of repose, Tapped density, Carr's compressibility file, Bulk density, Hausner’s ratios were assessed. Moreover, flow was described utilizing powder rheometer wherein delicate force transducer screens the forces created as consequence of the sample displacement, another technique FT4 powder rheometer. The Freeman Technology (FT4 powder rheometer) is intended to describe powders undergoing different circumstances in manners that look like wide scale creation climate. Techniques incorporate security and irregular flow rate, compressibility, shear cell, air circulation, porousness, divider contact and union. The FT4 has demonstrated application on the whole powders preparing ventures, including drugs, fine synthetic substances, cosmetics, food, additives and powder covering. The FT4 application connect to filling, hopper flow, Tablet pressure, wet granulation, end point, flow added substance determination and enhancement, moisture impacts, static change, feeding, stirring, separation, caking, processing, Wall grating, grip, hopper configuration etc.
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