用于生物医学应用的添加剂制造氧化锆基生物陶瓷

Sakthiabirami Kumaresan, Soundharrajan Vaiyapuri, Jin-Ho Kang, Nileshkumar Dubey, Geetha Manivasagam, Kwi-Dug Yun, Sangwon Park
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引用次数: 2

摘要

氧化锆因其优异的机械持久性和生物相容性而成为主要的重要陶瓷材料之一,这使其成为牙科和骨科应用的热门材料。这启发了生物医学工程师开发锆基生物陶瓷用于牙齿修复和修复由癌症、关节炎和创伤引起的负重骨缺损。增材制造(AM)正在被推广为一种模仿人体组织复杂结构的可能技术,最近的进展使其成为临床应用的合适选择。增材制造是一种自下而上的方法,可以为植入物、假体和支架制造的3D打印氧化锆生物陶瓷提供高分辨率。为了最大限度地发挥增材制造的临床潜力,世界范围内已经开始了大规模的研究,以重新格式化和优化生物医学应用的氧化锆生物陶瓷。本章提供了使用AM技术用于生物医学应用的氧化锆基生物陶瓷的全面总结,并强调了与氧化锆AM相关的挑战。
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Additive Manufactured Zirconia-Based Bio-Ceramics for Biomedical Applications
Zirconia was established as one of the chief vital ceramic materials for its superior mechanical permanency and biocompatibility, which make it a popular material for dental and orthopedic applications. This has inspired biomedical engineers to exploit zirconia-based bioceramics for dental restorations and repair of load-bearing bone defects caused by cancer, arthritis, and trauma. Additive manufacturing (AM) is being promoted as a possible technique for mimicking the complex architecture of human tissues, and advancements reported in the recent past make it a suitable choice for clinical applications. AM is a bottom-up approach that can offer a high resolution to 3D printed zirconia-based bioceramics for implants, prostheses, and scaffold manufacturing. Substantial research has been initiated worldwide on a large scale for reformatting and optimizing zirconia bioceramics for biomedical applications to maximize the clinical potential of AM. This book chapter provides a comprehensive summary of zirconia-based bioceramics using AM techniques for biomedical applications and highlights the challenges related to AM of zirconia.
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