甲状腺机能亢进与眼压和干眼有关

Madhuri Patil, M. Gitanjali
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摘要

Graves眼病(GO)又称甲状腺眼病(TED)、甲状腺功能障碍/甲状腺相关眼病(TAO),是Graves病最常见、最重要的甲状腺外表现,是一种自身免疫性疾病。材料与方法:这是一项为期2年的前瞻性研究。本研究共纳入60例甲状腺功能亢进患者,这些患者来自所有年龄组,不论性别,均在医院诊断为甲状腺眼病。眼部手术或药物史,近期使用隐形眼镜者,孕妇或哺乳期妇女。所有表现相似但未被证实为甲状腺眼病的病例和未报告随访的患者均被排除在研究之外。结果:共检查60例患者。在分析的60例病例中,女性居多,41-60岁年龄组甲状腺眼病发病率最高。最常见的表现是单侧。下直肌受累最多(48.3%),其次是内直肌(38.3%),上直肌(23.3%),外直肌受累最少(11.6%)。没有患者报告视力丧失。结论:干眼症和IOP升高是常见的结果,应认真处理。这种潜在的视力威胁情况在世界范围内都有,并且有许多需要认识到的功能和美容后果。甲亢与病情严重程度显著相关。
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Hyperthyroidism associated with intraocular pressure and dry eye
Graves’ orbitopathy/ophthalmopathy (GO) also known as thyroid eye disease (TED),dysthyroid/thyroid-associated ophthalmopathy (TAO), is an autoimmune disorder representing thecommonest and most important extrathyroidal manifestation of Graves’ disease. Materials andMethods: This is a prospective study conducted for 2 years. A total of 60 established cases ofHyperthyroidism of all Age groups with either gender subjects who were diagnosed with Thyroidorbitopathy at hospitals were included in this study. History of ocular surgery or medications, thosedemonstrating the recent use of contact lenses, pregnant or lactating women. All the cases withsimilar presentation not proved to be Thyroid Orbitopathy and patients who did not report for thefollow-up were excluded from the study. Result: A total of 60 patients were examined. Of the 60cases analyzed, female preponderance was noted and 41-60 years age group had the highestincidence of thyroid orbitopathy. The most common presentation was found to be unilateral. Inferiorrectus muscle was the commonest muscle involved with 48.3% followed by Medial rectus muscle38.3%, Superior rectus muscle 23.3%, and Lateral rectus muscle involved least with 11.6% indescending order. None of the patients reported a loss of vision. Conclusions: Dry eye andincreased IOP have commonly seen outcomes that should be managed diligently. This potentialsight-threatening condition is seen worldwide and has many functional and cosmetic consequencesthat need to be recognized. Hyperthyroidism was significantly associated with the severity.
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