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Clinical patterns of Uveitis in a Regional Eye Institute of North India 北印度地区眼科研究所葡萄膜炎的临床特点
Pub Date : 2021-08-31 DOI: 10.17511/jooo.2021.i04.02
Pratibha Malhotra, M. Kaur, I. Kaur, P. Kaur, N. Malhotra
Background: Uveitis encompasses many conditions, all characterized by inflammation of the uvealtract either directly or indirectly. It can occur at any age but predominantly affects patients in theworking-age group. Objective: To report the clinical pattern of Uveitis in North India. Settings andDesign: A prospective study in a regional eye institute. Methods: After taking informed consent,100 patients with Uveitis aged 20–60 years were recruited from eye OPD between 2012- 2014.Detailed history, complete ophthalmic examination, standard diagnostic laboratory tests andradiographic studies wherever required were made. Statistical analysis used: Descriptive.Results: The mean age being 41.55 years. There were 57% males and 43% females with 32%acute uveitis and 68% chronic uveitis cases. Anterior Uveitis was seen in 83% of patients, followedby posterior Uveitis (7%), pan-uveitis (6%) and intermediate Uveitis (4%). A definite associationwith the systemic disease was determined in 27% of cases. The most frequently observed systemicdiseases were ankylosing spondylitis, Tuberculosis and herpes zoster ophthalmicus (6% cases each).This was followed by HIV (3%), sarcoidosis (3%), ulcerative colitis (2%) and endophthalmitis (1%).No specific aetiology or association with systemic diseases could be established in 73% of cases. Inmost cases, the systemic disease was not suspected before eye involvement and was recognizedonly after the subsequent diagnostic procedures. Conclusion: The etiological diagnosis of Uveitis isoften challenging as there are marked variations in ocular and systemic signs and symptoms. Asignificant number of cases may unfold with the evolution of advanced techniques.
背景:葡萄膜炎包括多种情况,其特征都是葡萄膜直接或间接的炎症。它可以发生在任何年龄,但主要影响工作年龄组的患者。目的:报道印度北部葡萄膜炎的临床特点。背景与设计:一项地区眼科研究所的前瞻性研究。方法:选取2012- 2014年眼科门诊收治的葡萄膜炎患者100例,年龄20 ~ 60岁。详细的病史,完整的眼科检查,标准诊断实验室检查和放射学检查。使用的统计分析:描述性。结果:患者平均年龄41.55岁。急性葡萄膜炎占32%,慢性葡萄膜炎占68%,男性占57%,女性占43%。83%的患者出现前葡萄膜炎,其次是后葡萄膜炎(7%)、泛葡萄膜炎(6%)和中间葡萄膜炎(4%)。在27%的病例中确定了与全身性疾病的明确关联。最常见的全身性疾病为强直性脊柱炎、肺结核和眼带状疱疹(各占6%)。其次是HIV(3%)、结节病(3%)、溃疡性结肠炎(2%)和眼内炎(1%)。73%的病例没有明确的病因或与全身性疾病的关联。在大多数病例中,全身性疾病在眼部受累之前没有被怀疑,只有在随后的诊断程序后才被识别出来。结论:葡萄膜炎的病因诊断往往具有挑战性,因为其眼部和全身体征和症状有明显的变化。随着先进技术的发展,可能会出现相当数量的病例。
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引用次数: 0
Effect of donor and host factors on corneal graft transparency 供体和宿主因素对角膜移植物透明度的影响
Pub Date : 2021-08-31 DOI: 10.17511/jooo.2021.i04.01
Amisha Jain, H. Joshi, Nimish Jain, Cornea Cataract
Objective: To study the correlation between donor factors and recipients' factors on graft clarity.Materials and methods: The study comprised 30 cases of Keratoplasty surgery with a follow up of6 months. All donor corneas were evaluated by Konan specular microscope for endothelial cellcount; details of the donor like age, cause of death were noted. The patients were divided into twogroups, Group 1 had graft failure, and Group 2 had clear corneas. Observation and Result: Therewere 12 patients in group 1 and 18 patients in group 2 with six months of follow up. The meanendothelial cell count in group 1 was 1942.3/mm2, and group 2 was 2334.8/mm2. There is asignificant difference in the mean endothelial cell count between the two groups. On analysing theindication for Keratoplasty in two groups, the outcome was best for the corneal opacity group duringworst for the graft failure group. Conclusion: Donor endothelial cell count significantly influencedgraft outcome; rest donor factors (age, death enucleation interval, enucleation surgery interval)don't affect graft survival. Indication for Keratoplasty is a significant predictor of graft survival.
目的:探讨供体因素与受体因素对移植物清晰度的影响。材料与方法:本研究包括30例角膜移植术患者,随访6个月。所有供体角膜用Konan镜面显微镜观察内皮细胞计数;捐赠者的细节,比如年龄,死因都被记录了下来。患者分为两组,1组角膜移植失败,2组角膜清晰。观察与结果:1组12例,2组18例,随访6个月。1组内皮细胞平均计数为1942.3个/mm2, 2组内皮细胞平均计数为2334.8个/mm2。两组间平均内皮细胞计数差异有统计学意义。分析两组角膜移植术的适应证,角膜混浊组疗效最好,角膜移植失败组疗效最差。结论:供体内皮细胞计数对移植物预后有显著影响;其他供体因素(年龄、死亡、去核间隔、去核手术间隔)不影响移植物存活。角膜移植的指征是移植物存活的重要预测指标。
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引用次数: 0
A retrospective study to analyse the ocular morbidity in the slum-dwelling population of central India. 回顾性研究分析印度中部贫民窟人口眼部发病率。
Pub Date : 2021-08-31 DOI: 10.17511/jooo.2021.i04.03
Dr. Poorva Shrivastava, Dr Apoorva Soni, Dr. S. G. Ramesh Kumar, Dr. Lalit Shrivastava
Background: The study aimed to evaluate the prevalence of different ocular pathologies in theslum-dwelling population of central India and to find its correlations with socio-demographic factors.Methodology: The study was conducted as a cross-sectional study in 84 slum areas across Bhopal,Jabalpur and areas in the vicinity using a camp-based approach during the study period of 3 years.A total of 15478 participants attended the camp, and of them, 6177 patients had variousophthalmological conditions. A detailed history was obtained, and participants were subjected to acomplete ophthalmological examination. Based upon their diagnosis, they were prescribedtreatment. Referral to the tertiary care centre was done when needed. Results: The prevalence ofocular morbidities was 39.9%. The most common ocular morbidity documented in our study wasrefractive errors (22.7%). Proportions of lid pathologies were significantly higher in patientsbelonging to less than ten years of age (36.4%). In contrast, refractive errors were observed inhigher proportions of patients belonging to more than ten years of age (p<0.05). Pterygium ratiowas significantly higher in males, whereas ocular malignancies were higher in females (p<0.05).Proportions of almost all the ocular morbidities were substantially higher in patients with lowsocioeconomic status (p<0.05). Conclusion: The overall prevalence of ocular morbidities in theslum population is high. The most common ocular morbidity includes refractive error and allergicconjunctivitis. These morbidities correlated with age, gender and socioeconomic status. Werecommend periodic screening of the slum population across all age range to prevent long termcomplications and disabilities.
背景:本研究旨在评估印度中部贫民窟人口中不同眼部病变的患病率,并发现其与社会人口因素的相关性。研究方法:在为期3年的研究期间,采用以营地为基础的方法,在博帕尔、贾巴尔普尔和附近地区的84个贫民窟进行了横断面研究。共有15478名参与者参加了该营,其中6177名患者患有各种眼科疾病。获得了详细的病史,参与者接受了完整的眼科检查。根据他们的诊断,对他们进行了治疗。如有需要,可转介至三级护理中心。结果:眼病患病率为39.9%。在我们的研究中最常见的眼部疾病是屈光不正(22.7%)。10岁以下患者眼睑病变比例明显高于10岁以下患者(36.4%)。10岁以上患者屈光不正发生率较高(p<0.05)。男性患翼状胬肉的比例显著高于女性患眼部恶性肿瘤的比例(p<0.05)。社会经济地位低的患者几乎所有眼部疾病的比例都明显高于社会经济地位低的患者(p<0.05)。结论:贫民窟人群眼部疾病的总体患病率较高。最常见的眼部疾病包括屈光不正和过敏性结膜炎。这些发病率与年龄、性别和社会经济地位有关。我们建议对所有年龄段的贫民窟人口进行定期筛查,以防止长期并发症和残疾。
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引用次数: 0
Sleep-disordered breathing a neglected risk factor in primary open-angle glaucoma 睡眠呼吸障碍是原发性开角型青光眼被忽视的危险因素
Pub Date : 2021-08-31 DOI: 10.17511/jooo.2021.i04.04
Dr. Mandeep Kaur, D. Kaur, Dr. Jagdeepak Singh
Background: Sleep-disordered breathing (SDB) is accompanied by large swings in blood pressureand the repetitive hypoxic period during sleep, which may accelerate anoxic optic nerve damageseen in glaucoma. There are many associated risk factors in primary open-angle glaucoma (POAG),but recently, SDB, though a neglected one, is coming up as a risk factor. However, various studieshave reported controversial findings. Objective: To evaluate the relationship between SDB andPOAG. Design: A hospital-based case-control study. Methods: A total of 400 patients between 30–70 years were recruited from eye OPD between 2008- 2010. They were divided into two groups, 200cases with established POAG and 200 age and sex-matched healthy subjects with normal IOP in thecontrol group. Detailed history, complete ophthalmic and ENT examination was made along withBMI, blood pressure and neck girth measurement. Both groups were interviewed with aquestionnaire regarding SDB and were recorded on the Epworth sleepiness scale (ESS). Results:The mean age being 55.02 ± 8.66 in the POAG group and male predominance noted both in POAGand SDB patients with ESS> 10 was statistically significant (p < 0.05). Also, patients in the POAGgroup with ESS > 10 had more IOP and BMI, greater neck girth, high BP and more ENT problemswith p-value < 0,001, which is highly significant, thus showing the relationship between SDB andPOAG. Conclusions: Increased community awareness and earlier detection of glaucoma and itscorrelation with SDB results in decreased morbidity.
背景:睡眠呼吸障碍(SDB)伴随着血压的大幅波动和睡眠中反复的缺氧期,这可能加速青光眼中出现的缺氧视神经损伤。原发性开角型青光眼(POAG)有许多相关的危险因素,但SDB虽然是一个被忽视的危险因素,但最近却被认为是一个危险因素。然而,各种研究报告了有争议的发现。目的:探讨SDB与poag的关系。设计:以医院为基础的病例对照研究。方法:选取2008- 2010年眼科门诊患者400例,年龄30-70岁。他们被分为两组,200例已确诊的POAG和200例年龄和性别匹配的正常IOP的健康受试者作为对照组。详细的病史,完整的眼科和耳鼻喉科检查以及bmi,血压和颈围测量。两组均接受关于SDB的问卷调查,并以Epworth嗜睡量表(ESS)进行记录。结果:POAG组平均年龄为55.02±8.66岁,且POAG和SDB合并ESS患者bbb10均以男性为主,差异有统计学意义(p < 0.05)。同时,poag组ESS bbb10患者IOP和BMI更高,颈围更大,血压高,耳鼻喉科问题更多,p值< 0.001,具有高度显著性,说明SDB与poag之间存在相关性。结论:提高社区意识和早期发现青光眼及其与SDB的相关性可降低发病率。
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引用次数: 0
Comparison of conjunctival free autograft and Rotational flap technique in primary pterygium surgery: Visual changes and safety profiles 自体结膜游离移植和旋转皮瓣技术在原发性翼状胬肉手术中的比较:视觉变化和安全性
Pub Date : 2021-06-30 DOI: 10.17511/jooo.2021.i03.03
Pawan Chaurasia, Vaishali Chaurasia
Aims and objectives: To evaluate the postoperative symptomatic comfort, visual changes,complication and rate of recurrence in free conjunctival autograft and rotational flap technique inprimary pterygium surgery. Materials & Methods: This prospective study was conducted in 60 eyesof 60 patients, presented with primary progressive nasal pterygium larger than 1mm causingsymptomatic discomfort, astigmatism and cosmetic disfigurement. Patients were divided into twogroups randomly. In group A, patients with pterygium excision with free conjunctival autograft andgroup B, pterygium excision with rotation flap technique were included. Post-operative day 1symptomatic comfort (symptoms and signs), graft stability, corneal clarity and any complicationwere noted. Visual acuity (VA), auto-refracto keratometer measurements and detailedbiomicroscopic examinations, were performed preoperatively and postoperatively at 1month and 3months. Results: Most of the patients in our study were in the middle age group of 40-49 years(41.6%). Out of 60 patients, 35 were males (58.4%) and 25 were females (41.6%). Patients withoutdoor activities had a higher prevalence of pterygium (78.4%). The incidence of pterygium wasmore in the right eye (60%) than left eye (40%). Of the 60 patients, Grade I, II and III pterygiumwas 20%, 56.7% and 23.3% in group A and 16.7%, 63.3% and 20% in group B respectively. Themean symptomatic score was statistically significantly higher for group A for each factor (P<0.05).In the 3rd month, the overall patient’s satisfaction score was significantly higher in group B(P<0.05). Conclusion: Both surgical techniques were equally effective in terms of visual acuity,astigmatism and recurrence. The patient’s satisfaction score was significantly higher in the rotationflap technique group.
目的:评价自体结膜游离移植联合旋转瓣技术治疗原发性翼状胬肉的术后症状舒适度、视力变化、并发症及复发率。材料与方法:本前瞻性研究在60例60眼患者中进行,这些患者的原发性进行性鼻翼状胬肉大于1mm,导致症状性不适、散光和美容毁容。患者随机分为两组。A组采用自体结膜游离移植术进行翼状胬肉切除,B组采用旋转瓣技术进行翼状胬肉切除。观察术后第1天症状舒适(症状和体征)、移植物稳定性、角膜清晰度和任何并发症。术前、术后1个月和3个月分别进行视力(VA)、自动屈光角膜计测量和详细的生物显微镜检查。结果:本组患者以40 ~ 49岁中年人居多(41.6%)。60例患者中,男性35例(58.4%),女性25例(41.6%)。有户外活动的患者翼状胬肉患病率较高(78.4%)。右眼翼状胬肉的发生率(60%)高于左眼(40%)。60例患者中,A组I级、II级、III级翼状胬肉分别占20%、56.7%、23.3%,B组分别占16.7%、63.3%、20%。A组患者各因素的平均症状评分均高于对照组(P<0.05)。第3个月时,B组患者总体满意度得分显著高于对照组(P<0.05)。结论:两种手术方式在视力、散光和复发率方面效果相同。旋转皮瓣组患者满意度得分明显高于旋转皮瓣组。
{"title":"Comparison of conjunctival free autograft and Rotational flap technique in primary pterygium surgery: Visual changes and safety profiles","authors":"Pawan Chaurasia, Vaishali Chaurasia","doi":"10.17511/jooo.2021.i03.03","DOIUrl":"https://doi.org/10.17511/jooo.2021.i03.03","url":null,"abstract":"Aims and objectives: To evaluate the postoperative symptomatic comfort, visual changes,complication and rate of recurrence in free conjunctival autograft and rotational flap technique inprimary pterygium surgery. Materials & Methods: This prospective study was conducted in 60 eyesof 60 patients, presented with primary progressive nasal pterygium larger than 1mm causingsymptomatic discomfort, astigmatism and cosmetic disfigurement. Patients were divided into twogroups randomly. In group A, patients with pterygium excision with free conjunctival autograft andgroup B, pterygium excision with rotation flap technique were included. Post-operative day 1symptomatic comfort (symptoms and signs), graft stability, corneal clarity and any complicationwere noted. Visual acuity (VA), auto-refracto keratometer measurements and detailedbiomicroscopic examinations, were performed preoperatively and postoperatively at 1month and 3months. Results: Most of the patients in our study were in the middle age group of 40-49 years(41.6%). Out of 60 patients, 35 were males (58.4%) and 25 were females (41.6%). Patients withoutdoor activities had a higher prevalence of pterygium (78.4%). The incidence of pterygium wasmore in the right eye (60%) than left eye (40%). Of the 60 patients, Grade I, II and III pterygiumwas 20%, 56.7% and 23.3% in group A and 16.7%, 63.3% and 20% in group B respectively. Themean symptomatic score was statistically significantly higher for group A for each factor (P<0.05).In the 3rd month, the overall patient’s satisfaction score was significantly higher in group B(P<0.05). Conclusion: Both surgical techniques were equally effective in terms of visual acuity,astigmatism and recurrence. The patient’s satisfaction score was significantly higher in the rotationflap technique group.","PeriodicalId":112259,"journal":{"name":"Tropical Journal of Ophthalmology and Otolaryngology","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127062901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular Manifestations Of Carotid Cavernous Fistula and Clinical Outcome After Management 颈动脉海绵状瘘的眼部表现及治疗后的临床结果
Pub Date : 2021-06-30 DOI: 10.17511/jooo.2021.i03.01
Dr. Sirisha Gantela, Dr. N. Lakshmi Chowdary, Dr. M. Satyanarayana
Aim: The purpose of the study is to report the ocular manifestations of Carotid cavernous fistula. Toconfirm the diagnosis by radiological investigations and to evaluate the clinical outcome aftermanagement. Materials and Methods: Patients who presented to the ophthalmology departmentwith signs and symptoms of carotid-cavernous fistula were evaluated by clinical examinationfollowed by radiological investigations like ultrasound, Doppler, CT scan and MRI. They laterunderwent DSA ( Digital Subtraction Angiography) for confirmation followed by definitive treatment.Results: Out of four patients who had direct CCF, three cases were managed by endovascularembolization of the parent artery. The remaining one case was conservatively managed by carotidmassage as it was a low flow fistula and the patient also had Parkinson’s disease. Four cases thathad indirect CCF were managed by carotid massage. Complete closure of the fistula is seen in allcases. Patients were followed up for 1 month, 3 months and 6 months and clinical outcome wasevaluated. Conclusion: CCF should be suspected in the presence of arteriolised conjunctivalvessels, proptosis and audible bruit. Diagnosis is by radiological tests like ultrasonography, Doppler,CT scan and MRI. The confirmatory test is digital subtraction angiography (DSA). Direct CCF iseffectively treated with endovascular therapy by coiling the fistula and indirect CCF is managed bymanual compression. Early diagnosis and treatment can prevent sight-threatening complications.
目的:报道颈动脉海绵窦瘘的眼部表现。目的:通过影像学检查确认诊断并评价治疗后的临床结果。材料与方法:对就诊于眼科的颈动脉海绵窦瘘患者进行临床检查、超声、多普勒、CT、MRI等影像学检查。他们随后接受DSA(数字减影血管造影)确认,然后进行最终治疗。结果:在4例直接CCF患者中,3例通过血管内动脉栓塞治疗母动脉。其余1例因为低流量瘘管且患者同时患有帕金森病,采用颈动脉按摩保守治疗。通过颈动脉按摩治疗间接CCF 4例。所有病例均见瘘管完全闭合。随访1个月、3个月、6个月,观察临床结果。结论:结膜血管微细化、突出和可听杂音时应怀疑CCF。诊断是通过放射检查,如超声、多普勒、CT扫描和MRI。证实性检查是数字减影血管造影(DSA)。直接CCF可以通过血管内治疗有效地治疗,而间接CCF可以通过手动压迫来治疗。早期诊断和治疗可以预防威胁视力的并发症。
{"title":"Ocular Manifestations Of Carotid Cavernous Fistula and Clinical Outcome After Management","authors":"Dr. Sirisha Gantela, Dr. N. Lakshmi Chowdary, Dr. M. Satyanarayana","doi":"10.17511/jooo.2021.i03.01","DOIUrl":"https://doi.org/10.17511/jooo.2021.i03.01","url":null,"abstract":"Aim: The purpose of the study is to report the ocular manifestations of Carotid cavernous fistula. Toconfirm the diagnosis by radiological investigations and to evaluate the clinical outcome aftermanagement. Materials and Methods: Patients who presented to the ophthalmology departmentwith signs and symptoms of carotid-cavernous fistula were evaluated by clinical examinationfollowed by radiological investigations like ultrasound, Doppler, CT scan and MRI. They laterunderwent DSA ( Digital Subtraction Angiography) for confirmation followed by definitive treatment.Results: Out of four patients who had direct CCF, three cases were managed by endovascularembolization of the parent artery. The remaining one case was conservatively managed by carotidmassage as it was a low flow fistula and the patient also had Parkinson’s disease. Four cases thathad indirect CCF were managed by carotid massage. Complete closure of the fistula is seen in allcases. Patients were followed up for 1 month, 3 months and 6 months and clinical outcome wasevaluated. Conclusion: CCF should be suspected in the presence of arteriolised conjunctivalvessels, proptosis and audible bruit. Diagnosis is by radiological tests like ultrasonography, Doppler,CT scan and MRI. The confirmatory test is digital subtraction angiography (DSA). Direct CCF iseffectively treated with endovascular therapy by coiling the fistula and indirect CCF is managed bymanual compression. Early diagnosis and treatment can prevent sight-threatening complications.","PeriodicalId":112259,"journal":{"name":"Tropical Journal of Ophthalmology and Otolaryngology","volume":"08 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134535664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between type 2 diabetes mellitus and central corneal thickness: A cross-sectional study 2型糖尿病与角膜中央厚度的相关性:一项横断面研究
Pub Date : 2021-04-23 DOI: 10.17511/JOOO.2021.I02.03
Jigisha Desai
Background and Aim: Diabetes has emerged as an important global health concern because of itsvarious adverse effects on the ocular tissue. The present study was done to study the correlationbetween type 2 diabetes mellitus and central corneal thickness in patients coming to the tertiarycare institute of Gujarat, India. Material and Methods: The present study was conducted over 1year at the tertiary care institute of Gujarat, India.50 patients with type 2 diabetes mellituspreviously diagnosed by a physician on treatment and 50 age-matched controls who are non-diabetics on history and blood sugar levels were enrolled. The central corneal thickness wasmeasured using an ultrasound pachymeter using multiple reading single point modes by a singleperson. Results: The mean central corneal thickness in diabetics was 565 ± 21 micrometres and innon-diabetics was 517 ± 20 micrometres. The central corneal thickness was found to be higher inpatients with type 2 diabetes mellitus when compared to non-diabetics. Conclusion: Patients withtype 2 diabetes mellitus were found to have thicker corneas as compared to non-diabetics. Thisshould take into consideration while interpreting intraocular pressure and before any refractivesurgeries in diabetics.
背景和目的:糖尿病已成为一个重要的全球健康问题,因为它对眼部组织的各种不良影响。本研究旨在研究在印度古吉拉特邦三级医疗机构就诊的2型糖尿病患者与角膜中央厚度之间的关系。材料和方法:本研究在印度古吉拉特邦三级保健研究所进行了1年多的研究,纳入了50名以前由医生诊断正在治疗的2型糖尿病患者和50名年龄匹配的对照组,这些患者在病史和血糖水平上没有糖尿病。使用超声厚计测量角膜中央厚度,该厚计由一人使用多读单点模式。结果:糖尿病患者角膜中央厚度平均为565±21微米,非糖尿病患者角膜中央厚度平均为517±20微米。与非糖尿病患者相比,2型糖尿病患者角膜中央厚度更高。结论:2型糖尿病患者角膜较非糖尿病患者厚。在糖尿病患者进行任何屈光手术之前,在解释眼压时应考虑到这一点。
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引用次数: 0
Relationship between habits and precancerous lesions of the oral cavity – a clinicopathological study 习惯与口腔癌前病变的关系——一项临床病理研究
Pub Date : 2021-01-30 DOI: 10.17511/jooo.2021.i01.01
Dr. Ajay Kumar Yadlapalli, Dr. B Krishna Santosh, D. S. Reddy, Dr. Panda Veeranjaneyulu, Dr. Maroju Lakshmi Snehitha, Dr. Pothula Priyanka
Introduction: Oral cancers account for 3% of total malignancies. A research was conducted to findthe incidence, age, and sex distribution, clinical presentation, and the relationship between habitsand various premalignant lesions of the oral cavity. Methods: It was a hospital-based observationaland cross-sectional study, conducted in GSL Medical College, Rajamahendravaram from October2015 to April 2017. Individuals aged > 18 years, with leukoplakia, erythroplakia, blanched mucosawith or without fibrous bands and /or trismus suggestive of oral submucous fibrosis, bilateral whitishlesions with a reticular pattern suggestive of lichen planus, and ulcer against sharp tooth denturesuggestive of traumatic dental ulcers were taken. Individuals with frank oral malignancy, those withterminal diseases, those who did not submit informed consent were not considered. Results: Themajority of patients (33.33%) were aged between 51 – 60 years, belong (62.75%) to lowersocioeconomic status. Leukoplakia (64.7%) was a common clinical presentation. Most (49.02%) ofthe study patients presented with a burning sensation. When addictions were considered, 86.27% ofpatients were smokers, 23.53% were addicted to alcohol. Conclusion: Leukoplakia was thecommonest (64.71%) premalignant lesion, 51 – 60 years was the common age group. Premalignantlesions were most commonly seen among males, most of the study participants belong to low andmiddle socio-economic groups with a rural background. Diabetes mellitus was the most commoncomorbidity associated with premalignant lesions.
口腔癌占所有恶性肿瘤的3%。本文对口腔恶性病变的发病率、年龄、性别分布、临床表现及习惯与口腔恶性病变的关系进行了研究。方法:2015年10月至2017年4月在印度拉贾姆亨德拉瓦拉姆市GSL医学院进行了一项以医院为基础的观察性横断面研究。年龄> 18岁,伴有白斑、红斑、黏膜变白,伴有或不伴有纤维带和/或牙锁,提示口腔粘膜下纤维化,双侧呈网状的白色病变提示扁平苔藓,以及提示外伤性口腔溃疡的尖锐假牙溃疡。口腔恶性肿瘤患者、绝症患者、未提交知情同意书者不在考虑之列。结果:51 ~ 60岁的患者占33.33%,社会经济地位较低的占62.75%。白斑(64.7%)是常见的临床表现。大多数(49.02%)患者表现为烧灼感。当考虑成瘾时,86.27%的患者为吸烟者,23.53%的患者为酒精成瘾者。结论:白斑是最常见的恶性前病变(64.71%),51 ~ 60岁为常见年龄组。恶性前病变最常见于男性,大多数研究参与者属于农村背景的中低社会经济群体。糖尿病是最常见的与癌前病变相关的合并症。
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引用次数: 0
Wriggly creatures coming out of eye: case report on human ocular thelaziasis 人眼虫病1例报告
Pub Date : 2020-12-31 DOI: 10.17511/JOOO.2020.I08.05
A. Tripathi, Sonali Bhalla
Ocular Thelaziasis is an arthropod-borne, zoonotic disease of the eye affecting the conjunctival sac,lacrimal duct, and lacrimal gland caused by a nematode of the genus Thelazia. Thelazia species aretransmitted by different species of Muscidae, which are a family of flies with worldwide distribution.The present study reports a case of human ocular Thelaziasis in a 13-year-old female patient.Species Thelazia callipaeda was confirmed based on microbiological examination. The patient wastreated with anti-helminthic drugs and was relieved of the symptoms without recurrence.
眼锥虫病是一种节肢动物传播的人畜共患疾病,由眼锥虫属线虫引起,影响结膜囊、泪管和泪腺。蝇科是一种分布在世界各地的蝇科,它通过不同种类的蝇类传播。本研究报告一例13岁女性患者的人眼寄生虫病。通过微生物学鉴定,确定了该物种为callipaeda。患者经抗虫药物治疗后症状缓解,无复发。
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引用次数: 1
A clinical study to determine the effects of adenoidectomy in cases of secretory otitis media in school going children 确定腺样体切除术对学龄期儿童分泌性中耳炎的影响的临床研究
Pub Date : 2020-12-31 DOI: 10.17511/JOOO.2020.I08.01
B. Santosh, K. Sumanth, P. Veeranjaneyulu, B. Deepthi, K. Mamatha
Introduction: Secretory Otitis media (SOM) is the leading cause of hearing loss in children. Despitenumerous studies on the prevention and treatment of SOM during the past decades, itsmanagement remains challenging and controversial. A study was conducted to find the effect ofadenoidectomy in cases of SOM with hypertrophied adenoids and to determine the effect ofadenoidectomy on hearing as assessed by the pure tone and impedance audiometry. Material andMethods: Children aged 5 – 12 years, diagnosed as SOM with adenoid hypertrophy were included.The study was conducted from April 2019 to May 2020, in the department of ENT, GSL MedicalCollege. A detailed history and clinical examination were done. Investigations such as pure toneaudiogram, impedance audiometry, X-ray nasopharynx, and diagnostic nasal endoscopy were carriedout to confirm the diagnosis. Results: Out of the 50 participants, a maximum (60%) belonged tothe 5 – 7 years age group, the male-female ratio was 1.2. Hard of hearing was a common symptomin 66%, tonsillitis, and sinusitis in 36% and 18% respectively. On pure tone audiometry, the averagehearing loss was 24.95dB. Conclusion: Adenoidectomy in children having hypertrophied adenoidswith SOM, not only relieves Eustachian tube obstruction but also removes the source of infection.This leads to clearance of middle ear effusion and improvement in hearing postoperatively.
分泌性中耳炎(SOM)是儿童听力损失的主要原因。尽管在过去的几十年里对SOM的预防和治疗进行了大量的研究,但其管理仍然具有挑战性和争议性。本研究旨在探讨腺样体切除术对SOM伴腺样体肥大的影响,并通过纯音和阻抗听力学评估腺样体切除术对听力的影响。材料与方法:5 - 12岁,诊断为SOM伴腺样体肥大的儿童。该研究于2019年4月至2020年5月在GSL医学院耳鼻喉科进行。详细的病史和临床检查。通过纯音听力学、阻抗听力学、鼻咽x线及诊断性鼻内窥镜检查证实诊断。结果:50名参与者中,最大(60%)属于5 - 7岁年龄组,男女比例为1.2。耳聋是常见的症状,占66%,扁桃体炎和鼻窦炎分别占36%和18%。在纯音听力测试中,平均听力损失为24.95dB。结论:腺样体增生伴SOM患儿行腺样体切除术,不仅可以缓解咽鼓管阻塞,而且可以消除感染源。这导致中耳积液的清除和术后听力的改善。
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Tropical Journal of Ophthalmology and Otolaryngology
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