Artem Goncharov, Hyou-Arm Joung, Rajesh Ghosh, Gyeo-Re Han, Zachary S. Ballard, Quinn Maloney, Alexandra Bell, Chew Tin Zar Aung, O. Garner, D. Di Carlo, Aydogan Ozcan
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Fluorescence-based multiplexed point-of-care sensor using deep learning
We present a multiplexed paper-based point-of-care sensor processed by a hand-held fluorescence reader and neural networks that quantify three cardiovascular disease biomarkers from human serum samples, achieving a limit-of-detection of ≤0.52 ng/mL for each biomarker.