帕金森病患者的皮肤病学问题

Muhammad Pervaiz, N. Gull, Sma Merchant, B. Arif, A. Naz, M. Waheed, S. Raza, S. Taj, I. Ali
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引用次数: 1

摘要

目的:确定帕金森病患者脂溢性皮炎、大疱性类天疱疮、酒渣鼻和黑色素瘤的发病率。横断面观察性研究2020年5月13日至2022年4月13日,在巴基斯坦拉合尔巴利亚国际医院。总共有80名帕金森病患者被确诊为皮肤病。根据Hoehn Yahr分期标准(H-Y分期)确定疾病严重程度。分别通过皮脂生成水平、热/冷潮红试验、免疫荧光和活检评估对脂溢性皮炎、酒糟、大疱性类天疱疮和黑色素瘤进行皮肤特征和疾病诊断。将测试结果与对照受试者进行比较。采用Chi2和学生t检验来检验结果的显著性。在80名患者中,有44名皮肤疾病呈阳性。脂溢性皮炎的发生率为31.2%,而酒渣鼻、大疱性类天疱疮和黑色素瘤的发生率分别为15%、6.2%和2.5%。皮肤疾病在帕金森病患者中比在对照人群中更为普遍。该研究邀请在这一领域的进一步研究,以提高患者的生活质量。
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DERMATOLOGICAL ISSUES IN PATIENT WITH PARKINSON’S DISEASE
To determine the incidence rate of seborrheic dermatitis, bullous pemphigoid, rosacea, and melanoma among the patients diagnosed with Parkinson's Disease. A cross-sectional, observational study. From 13th May 2020 to 13th April 2022 at Bahria International Hospital, Lahore, Pakistan. A total of 80 patients with confirmed Parkinson's disease were evaluated for skin disorders. Disease severity was confirmed through Hoehn Yahr staging criteria (H-Y stage). Skin characteristics and disease diagnosis was made through finding sebum production levels, hot/cold flush test, immunofluorescence, and biopsy evaluation for seborrheic dermatitis, rosacea, bullous pemphigoid, and melanoma, respectively. The test results were compared with the control subject. Chi2 and student t-test was used to find the significance of the results. Out of 80, 44 patients were positive for skin disorders. The incidence of seborrheic dermatitis was found in 31.2% of patients whereas rosacea, bullous pemphigoid, and melanoma were found in 15%, 6.2%, and 2.5% of patients, respectively. Skin disorders are highly prevalent among Parkinson’s disease patients than in the control population. The study invites further research in this area so that the quality of life of patients could be improved.
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