一种新型磁刺激系统:磁谐波多周期刺激(MHMS)分析

S. Goetz, T. Weyh, H. Herzog
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引用次数: 3

摘要

磁刺激如今已成为研究和临床应用的标准手段。但现有的系统仍然存在一些重大问题;这些包括极端的能量无效和刺激特性的灵活性差。在接下来的文本中,我们分析了一种新的时域刺激装置的自由度。由于在现有商业系统中实现该特性的简单性,该方法具有很高的潜力。很久以前,一个类似的原理已经应用于一个刺激装置,但被故意过阻尼以模拟单相系统,因此在能量上毫无意义。对于目前的工作,替代设计被实现到一个复杂的仿真模型中,以预测其性能。一个实质性的好处是,例如,降低刺激线圈内产生神经动作电位所需电流的阈值的可行性。因此,能量影响与振幅呈均匀二次关系,特别是线圈加热的减少是显著的。更精确地控制神经反应和进入更复杂的峰值模式领域的机会是另一个特殊的属性。这个概念的实现似乎相当简单,然而人们发现它的影响是巨大的。但这并不妨碍这样一个事实,即发现和解释需要改变对归纳刺激的刺激作用的思考。
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Analysis of a novel magnetic stimulation system: Magnetic harmonic multi-cycle stimulation (MHMS)
Magnetic stimulation is nowadays a standard instrument in research as well as clinical applications. But available systems still have some vital problems; these include the extreme energetic ineffectiveness and the poor flexibility of stimulation properties. In the following text we analyse a new degree of freedom for stimulation devices in the time domain. This approach owes its high potential from the simplicity to implement this feature in existing commercial systems. A similar principle has already been applied for a stimulation device long time ago, but was intentionally overdamped to mimic a monophasic system and therefore energetically meaningless. For the current work, the alternative design was implemented into a sophisticated simulation model to predict its properties. A substantial benefit is for instance the feasibility to lower the threshold of the required current within the stimulation coil for creating nervous action potentials dramatically. Accordingly, the energetic impact with its even quadratic relation to the amplitude and especially the reduction of the coil heating are remarkable. The opportunity to control the nervous reaction more precisely and to gain access to the field of more complex spiking patterns is another special attribute. The realization of the concept seems reasonably simple, whereas the impact was found to be enormous. But this shall not block the view of the fact that the discovery and the explanation needs a change of thinking about the stimulating effect of inductive stimulation.
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