生物学中微观结构的几何驱动可视化

K. Mosaliganti, R. Machiraju, Kun Huang
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引用次数: 1

摘要

生物学中有天然的几何模式。例如,组织层的差异主要体现在红细胞、细胞核、细胞质等微结构成分的空间分布、大小和排列。通过使用n点相关函数,表达可视化涉及发现特征空间,这些特征空间可以估计和空间描绘显著组织特有的成分分布。这些函数提供用于设置有用传递函数的特征空间。我们获得了小鼠乳腺导管上皮细胞衬里和斑马鱼胚胎中进化结构的深刻的三维可视化。这些是分别从光学和共聚焦显微镜扫描仪获得的大数据集。
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Geometry-driven visualization of microscopic structures in biology
There are natural geometric patterns in biology. Tissue layers, for example, differ mainly in the spatial distributions, size and packing of microstructure components such as the red blood cells, nuclei and cytoplasm etc. Expressive visualization by using the N-point correlation functions, involves the discovery of feature spaces that estimate and spatially delineate component distributions unique to a salient tissue. These functions provide feature spaces that are used to set useful transfer functions. We obtain insightful 3D visualizations of the epithelial cell lining in mouse mammary ducts and evolving structures in a zebrafish embryo. These are large datasets acquired from light and confocal microscopy scanners respectively.
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