{"title":"一种新型聚合物的合成:结构表征、抗菌和抗增殖活性","authors":"N. Çankaya","doi":"10.32571/ijct.1197666","DOIUrl":null,"url":null,"abstract":"In this study, homo-polymerization of N-(4-nitrophenyl) acrylamide (NPA) monomer was performed and firstly poly(NPA) homopolymer was synthesized in the literature. The structure of synthesized homopolymer was chemically characterized by FT-IR, 1H-NMR and 13C-NMR spectroscopic techniques and elemental analysis. Thermal behavior was investigated with DSC, and TGA/DTA/DTG simultaneous system. Biologically, antimicrobial activity (E. coli, S. aureus, B. megaterium, E. aeroginosa, C. tropicalis) test research was performed. Followed the cytotoxic effect of polymer was investigated using XTT assay on HeLa cells.","PeriodicalId":267255,"journal":{"name":"International Journal of Chemistry and Technology","volume":"48 5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A new polymer synthesis: structural characterization, antimicrobial and antiproliferative activity\",\"authors\":\"N. Çankaya\",\"doi\":\"10.32571/ijct.1197666\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this study, homo-polymerization of N-(4-nitrophenyl) acrylamide (NPA) monomer was performed and firstly poly(NPA) homopolymer was synthesized in the literature. The structure of synthesized homopolymer was chemically characterized by FT-IR, 1H-NMR and 13C-NMR spectroscopic techniques and elemental analysis. Thermal behavior was investigated with DSC, and TGA/DTA/DTG simultaneous system. Biologically, antimicrobial activity (E. coli, S. aureus, B. megaterium, E. aeroginosa, C. tropicalis) test research was performed. Followed the cytotoxic effect of polymer was investigated using XTT assay on HeLa cells.\",\"PeriodicalId\":267255,\"journal\":{\"name\":\"International Journal of Chemistry and Technology\",\"volume\":\"48 5 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Chemistry and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32571/ijct.1197666\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Chemistry and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32571/ijct.1197666","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A new polymer synthesis: structural characterization, antimicrobial and antiproliferative activity
In this study, homo-polymerization of N-(4-nitrophenyl) acrylamide (NPA) monomer was performed and firstly poly(NPA) homopolymer was synthesized in the literature. The structure of synthesized homopolymer was chemically characterized by FT-IR, 1H-NMR and 13C-NMR spectroscopic techniques and elemental analysis. Thermal behavior was investigated with DSC, and TGA/DTA/DTG simultaneous system. Biologically, antimicrobial activity (E. coli, S. aureus, B. megaterium, E. aeroginosa, C. tropicalis) test research was performed. Followed the cytotoxic effect of polymer was investigated using XTT assay on HeLa cells.
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