{"title":"固体脂质纳米颗粒与硬脂酸稳定与硬脂酸钇","authors":"A. Shirokikh, M. Koroleva, E. Yurtov","doi":"10.37614/2307-5252.2021.2.5.056","DOIUrl":null,"url":null,"abstract":"In this work, we studied the effect of yttrium stearate on the physicochemical properties of dispersions of solid lipid nanoparticles composed of stearic acid stabilized with nonionic surfactants (Tween 60, Span 60). The results showed that an increase in the concentration of yttrium stearate leads to increasing kinetic stability and decreasing the average size of the aggregates. Along with this, the average size of single particles remains practically unchanged and amounts to 35±5 nm.","PeriodicalId":438304,"journal":{"name":"Transaction Kola Science Centre","volume":"11 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Solid lipid nanoparticles with stearic acid stabilized with yttrium stearate\",\"authors\":\"A. Shirokikh, M. Koroleva, E. Yurtov\",\"doi\":\"10.37614/2307-5252.2021.2.5.056\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this work, we studied the effect of yttrium stearate on the physicochemical properties of dispersions of solid lipid nanoparticles composed of stearic acid stabilized with nonionic surfactants (Tween 60, Span 60). The results showed that an increase in the concentration of yttrium stearate leads to increasing kinetic stability and decreasing the average size of the aggregates. Along with this, the average size of single particles remains practically unchanged and amounts to 35±5 nm.\",\"PeriodicalId\":438304,\"journal\":{\"name\":\"Transaction Kola Science Centre\",\"volume\":\"11 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Transaction Kola Science Centre\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37614/2307-5252.2021.2.5.056\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Transaction Kola Science Centre","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37614/2307-5252.2021.2.5.056","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Solid lipid nanoparticles with stearic acid stabilized with yttrium stearate
In this work, we studied the effect of yttrium stearate on the physicochemical properties of dispersions of solid lipid nanoparticles composed of stearic acid stabilized with nonionic surfactants (Tween 60, Span 60). The results showed that an increase in the concentration of yttrium stearate leads to increasing kinetic stability and decreasing the average size of the aggregates. Along with this, the average size of single particles remains practically unchanged and amounts to 35±5 nm.
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