利用MRI神经成像技术早期检测阿尔茨海默病的深度学习方法

M. Bhargavi, Bharani Prabhakar
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摘要

阿尔茨海默病是一种神经退行性疾病,也是进行性痴呆最普遍的形式之一。阿尔茨海默病会导致大脑萎缩和脑细胞受损,目前尚无治疗方法。早期发现有助于评估和实施适当的治疗,从而减缓疾病的进展。最近,通过神经影像学对轻度认知障碍(MCI)患者进行渐进式监测已成为早期发现的重要手段。最常用的神经成像技术是核磁共振成像(MRI)。监测被诊断为轻度认知障碍的人的目的是,被诊断为轻度认知障碍的人更有可能转变为阿尔茨海默氏症。深度学习模型已被证明是非常有效的,并在神经成像分析中显示出强大的性能。深度学习技术被用于评估阿尔茨海默病的进展,最近由于其值得称赞的性能而获得了巨大的普及。在本文中,我们提出了一项关于深度学习技术在阿尔茨海默病早期检测和进展中的应用研究。这项研究的重点是利用深度学习模型和核磁共振神经成像技术早期检测阿尔茨海默氏症的最新进展。
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Deep Learning Approaches for Early Detection of Alzheimer's Disease using MRI Neuroimaging
Alzheimer's disease is a neurodegenerative disorder and one of the most prevalent forms of progressive Dementia. Alzheimer's disease does not have any cure as it leads to brain shrinkage and damage of the brain cells. Early detection can aid in assessing and administering suitable treatment that can slow down disease progression. Progressive monitoring of individuals diagnosed with Mild Cognitive Impairment (MCI) through neuroimaging has gained considerable interest recently for early detection. The most popular neuroimaging used being the Magnetic Resonance Imaging (MRI). The intention of monitoring individuals diagnosed with MCI is that, MCI diagnosed are more likely to get converted to Alzheimer's. Deep learning models have proven to be very effective and shown powerful performance in neuroimaging analytics. Deep learning techniques have been employed over brain MRI for assessing Alzheimer's disease progression and gained immense popularity in recent times due to its commendable performance. In this paper, we present a study on the applications of Deep learning techniques in early detection and progression of Alzheimer's disease. The study focuses on recent advances in the early detection of Alzheimer's using Deep learning models and MRI neuroimaging.
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