模拟生物组织凝胶胶模体的声学和热性能评价

G. Cortela, K. M. Lima, L. Maggi, C. Negreira, W. Pereira
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引用次数: 3

摘要

研制了一种水凝胶(结冷胶)组织模拟材料(TMM)。对其声学和热性能进行了表征。水凝胶与不同大小的玻璃球结合。在20 ~ 45℃的温度范围内,得到了声学特性(衰减系数和声速)的函数。在相同的温度范围内,用标准混合法实验确定了比热。衰减系数与频率呈准线性关系,如大多数哺乳动物组织。平均值为0.59f 0.85 dB·cm-1,温度为30℃,频率范围为1 ~ 10MHz。结果表明,所开发的TMM具有多种应用潜力:开发标准剂量学技术,验证数值模型和确定热疗装置的功效。
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Evaluation of acoustic and thermal properties of gellan-gum phantom to mimic biological tissue
A hydrogel-based (gellan gum) tissue mimicking material (TMM) was developed. Its acoustic and thermal properties were characterized. The hydrogel was combined with different sizes of glass spheres. The acoustic properties (attenuation coefficient and the speed of sound) were obtained as a function of the temperature range 20 to 45° C. Specific heat was determined experimentally by the standard mixture method for the same temperature range. The attenuation coefficient presented a quasi-linear dependence on the frequency, such as the most of mammalian tissues. The mean value was 0.59f 0,85 dB·cm-1, at 30° C from 1 to 10MHz. The results suggest that the developed TMM has potential for several applications: development of standard dosimetry techniques, validation numerical models and determination the efficacy of hyperthermia devices.
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