生物医学期刊科学论文中的置信区间和精确p值

S. V. Mylnikov
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引用次数: 0

摘要

国际医学期刊编辑委员会建议对获得的数据进行量化,并提供适当的测量误差指标。专业统计学家普遍认为,有必要在出版物中提供精确的p值,而不将其与任何阈值(临界值)相关联。巧合间隔是非常有用的。对于连续型随机变量,不仅对样本均值,对中位数、标准差、不对称性、峰度、变异系数等指标也要进行分析。对于离散随机变量,不仅对于频率,而且对于大多数流行病学指标-比值比,阳性和阴性预测值。回归分析应以构建所有系数的置信区间以及在图上表示预测区间结束。在方差分析中评估"因素影响的强度"的情况下,这一指标也必须有一个置信区间。指定研究过程中获得的确切p值可以增加已发表文章被纳入meta分析的概率。对于上述指标的大多数计算,MS Office软件包、其插件或位于免费互联网资源上的计算器就足够了。
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Confidence intervals and precise p-value in a scientific paper in a biomedical journal
The International Committee of Medical Journals Editors recommends that the data obtained be quantified and presented with appropriate indicators of measurement errors. There is a widespread belief among professional statisticians that it is necessary to present precise p-values in publications without correlating them with any threshold (critical) values. The coincidence intervals are extremely informative. For continuous random variables, not only for the sample mean, but also for other indicators: median, standard deviation, asymmetry, kurtosis and coefficient of variation. For discrete random variables, not only for frequency, but also for most epidemiological indicators – the odds ratio, positive and negative predictive values. Regression analysis should end with the construction of confidence interval for all coefficients, as well as the indication of predictive intervals on the graph. In the case of assessing the “strength of the influence of the factor” in the analysis of variance, a confidence interval for this indicator is also obligate. Specifying the exact p-value obtained during the study increases the probability of the published article being included in the meta-analysis. For most calculations of the above-mentioned indicators, the MS Office package, plug-ins to it or calculators located on freely available Internet resources are sufficient.
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