揭示信号转导通路的意义:癌症发展和进展的关键参与者

Emad Fadhal
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引用次数: 2

摘要

信号转导通路通过调节各种细胞过程在癌症的发生和进展中发挥核心作用。这些信号通路的失调在癌细胞中很常见,并有助于它们不受控制的生长和生存。因此,靶向这些异常信号通路已成为防止癌细胞增殖和促进治疗结果的一种有希望的策略。本研究强调了信号通路激活和调控在肿瘤生物学中的重要作用。此外,我们的研究结果还鉴定出了PIK3CA、EGFR、AKT1、MAP2K1、AR、JAK2等致癌基因
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" Unraveling The Significance Of Signal Transduction Pathways: Key Players In Cancer Development And Progression "
Signal transduction pathways play a central role in cancer development and progression by regulating various cellular processes. Dysregulation of these signaling pathways is common in cancer cells and contributes to their uncontrolled growth and survival. Targeting these aberrant signaling pathways has therefore emerged as a promising strategy to prevent cancer cell proliferation and promote therapeutic outcomes. This study highlights the critical role of signaling pathway activation and regulation in cancer biology. Furthermore, our results identified oncogenes such as PIK3CA, EGFR, AKT1, MAP2K1, AR, JAK2
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