Krati Mehrotra, Molisha Bhandari, Shruti Sharma, Niti Khunger
{"title":"生殖器和生殖器外LSA与皮肤镜特征共存","authors":"Krati Mehrotra, Molisha Bhandari, Shruti Sharma, Niti Khunger","doi":"10.25259/ijpgd_15_2023","DOIUrl":null,"url":null,"abstract":"Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis, primarily involving the anogenital region, and sometimes extragenital sites (15–20%). Rarely, patients can present with only extragenital lesions (2.5%). A 50-year-old female presented with depigmented lesions on vulva, bilateral knees and legs for 1½ years. Dermoscopy showed patchy white structureless areas with follicular plugs and histopathological examination revealed focal vacuolar degeneration of the basal layer and hyalinisation in the papillary dermis, with mild perivascular lymphohistiocytic inflammation, helping confirm the diagnosis of genital and extragenital LSA. Thus, the authors elaborate the rarity of coexistence of genital and extragenital LSA in a single patient and the use of dermoscopy as a tool in its diagnosis.","PeriodicalId":339918,"journal":{"name":"Indian Journal of Postgraduate Dermatology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Coexistence of Genital and Extragenital LSA with Dermoscopic Features\",\"authors\":\"Krati Mehrotra, Molisha Bhandari, Shruti Sharma, Niti Khunger\",\"doi\":\"10.25259/ijpgd_15_2023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis, primarily involving the anogenital region, and sometimes extragenital sites (15–20%). Rarely, patients can present with only extragenital lesions (2.5%). A 50-year-old female presented with depigmented lesions on vulva, bilateral knees and legs for 1½ years. Dermoscopy showed patchy white structureless areas with follicular plugs and histopathological examination revealed focal vacuolar degeneration of the basal layer and hyalinisation in the papillary dermis, with mild perivascular lymphohistiocytic inflammation, helping confirm the diagnosis of genital and extragenital LSA. Thus, the authors elaborate the rarity of coexistence of genital and extragenital LSA in a single patient and the use of dermoscopy as a tool in its diagnosis.\",\"PeriodicalId\":339918,\"journal\":{\"name\":\"Indian Journal of Postgraduate Dermatology\",\"volume\":\"55 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Postgraduate Dermatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/ijpgd_15_2023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Postgraduate Dermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/ijpgd_15_2023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Coexistence of Genital and Extragenital LSA with Dermoscopic Features
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory dermatosis, primarily involving the anogenital region, and sometimes extragenital sites (15–20%). Rarely, patients can present with only extragenital lesions (2.5%). A 50-year-old female presented with depigmented lesions on vulva, bilateral knees and legs for 1½ years. Dermoscopy showed patchy white structureless areas with follicular plugs and histopathological examination revealed focal vacuolar degeneration of the basal layer and hyalinisation in the papillary dermis, with mild perivascular lymphohistiocytic inflammation, helping confirm the diagnosis of genital and extragenital LSA. Thus, the authors elaborate the rarity of coexistence of genital and extragenital LSA in a single patient and the use of dermoscopy as a tool in its diagnosis.