基于多目标模型的部分数据关节三维重建:针对患者的膝关节植入物设计

Jean-Rassaire Fouefack, G. Dardenne, Bhushan S Borotikar, Tinashe Ernest Mutsvangwa, V. Burdin
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摘要

在临床常规中,三维(3D)骨几何形状的捕获对于手术计划,种植体放置和术后评估至关重要。然而,准确的膝关节三维重建来估计患者的特定特征仍然是一个挑战,尽管它已经被广泛研究。在这种情况下,统计形状模型(SSM)已被用于从部分观察中重建全局形状,基于它们捕获不同患者解剖变异的能力。然而,这些研究纳入了单对象ssm,这限制了它们在分析局部骨形态方面的应用,因此它们缺乏在关节水平上分析人体解剖的能力。本文采用动态多目标高斯过程模型(DMO-GPM)和基于马尔可夫链蒙特卡罗(MCMC)的模型拟合算法,提出了一种基于多目标的膝关节三维重建框架。膝关节重建结果显示,膝关节与原膝关节的表面距离平均误差为1.81±0.37 mm,最大误差为3.31 mm。结果表明,该方法能够准确地重建膝关节,尤其是关节接触面周围。这是至关重要的,因为植入物设计所需的大多数患者特定特征都使用该区域的地标。结果表明,该方法具有鲁棒性和准确性,可用于个性化膝关节植入物的设计。
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3D reconstruction of joints from partial data using multi-object-based model: Towards a patient-specific knee implant design
In clinical routine, the capture of three-dimensional (3D) bone geometry is crucial for surgical planning, implant placement and postoperative evaluation. Nevertheless, accurate 3D reconstruction of the knee joint for the estimation of patient-specific features remains a challenge, although it has been widely studied. In this context, statistical shape models (SSM) have been used to reconstruct a global shape from partial observations, based on their ability to capture the anatomical variation from different patients. However, these studies incorporate single object SSMs which limit their application for analyzing local bone morphology and thus they lack the capacity to analyze the human anatomy at the joint level. In this paper, we present a multi-object based framework for the 3D reconstruction of the knee joint using a dynamic multi-object Gaussian process model (DMO-GPM) and an adapted Markov Chain Monte Carlo (MCMC) based model fitting algorithm.The knees were reconstructed with an average mean square error of 1.81±0.37 mm and maximum error of 3.31 mm corresponding to the surface-to-surface distance between the predicted and original knees. The results show that the knee is accurately reconstructed, especially around the joint contact surfaces. This is crucial because most of the patient- specific features required for the implant design, use landmarks in this area. The results suggest that the approach is robust and accurate to design personalized knee implants.
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