两个指数可以近似地表示四百二种氨基酸的性质

C. Hagerty, I. Muchnik, C. Kulikowski, Sung-Hou Kim
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引用次数: 6

摘要

我们开发了一种涉及非线性转换的新颖通用技术,以两个简单可见的指数的形式总结了Nakai数据库中包含的四百二种氨基酸性质。与线性方法相比,该技术对原始数据的表示具有更高的保真度,并且氨基酸的分布一方面说明了它们对大小和疏水性的依赖,另一方面说明了它们对属于环与链的偏好。
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Two indices can approximate four hundred and two amino acid properties
We have developed a novel, general technique involving nonlinear transformation that summarizes the four hundred and two amino acid properties contained in the Nakai database in the form of two simply visualizable indices. The technique yields a higher fidelity of representation of the original data than linear methods, and results in a distribution of the amino acids which illustrates their dependence on size and hydrophobicity properties on the one hand, and their preference for belonging to loops vs. strands, on the other.
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