青少年腹膜和生殖器结核:一个具有挑战性的诊断

Sofia Ferrito, Rita Marques, Maria Cabral, F. Nunes, Margarida Pinto
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摘要

简介:约20%的病例出现肺外表现。腹膜和生殖器结核并不常见,特别是在没有任何合并症的儿童中。病例报告:一名健康的14岁女孩,主诉体重减轻、厌食、腹痛和发烧。检查时,她发热,腹部反跳压痛和腹胀。超声检查报告腹腔积液,纤维蛋白束和附件区复杂的囊性病变。剖腹探查发现多发腹膜囊肿,脓性渗出伴双侧输卵管脓肿。培养分离结核分枝杆菌,确诊腹膜结核。开始抗结核四联疗法及糖皮质激素治疗,临床反应良好。结论:腹膜和生殖器结核在儿童中并不常见,但死亡率和不孕率高。由于非特异性的临床、实验室或放射学检查结果,诊断常常被延误。该报告强调,为了准确和早期诊断,需要有一个大的疾病可疑指数。
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Peritoneal and genital tuberculosis in an adolescent: A challenging diagnosis
Introduction: Extra-pulmonary manifestations of tuberculosis occur in about 20% of cases. Peritoneal and genital tuberculosis are uncommon, especially in children without any comorbidity. Case report: A previously healthy 14-year-old girl, presented complaints of weight loss, anorexia, abdominal pain and fever. On examination, she was febrile, with rebound abdominal tenderness and abdominal distension. Ultrasonography reported peritoneal fluid, fibrin strands and complex cystic lesions in the adnexal region. Laparotomy evidenced multiple peritoneal cysts, purulent exudate with bilateral pyosalpinx. Mycobacterium tuberculosis was isolated in culture and confirmed the diagnosis of Peritoneal Tuberculosis. Antituberculous quadruple therapy and corticosteroids were started, with good clinical response. Conclusions: Peritoneal and genital tuberculosis are uncommon in children, but have high fatality and infertility rate. Due to the nonspecific clinical, laboratory or radiology findings, diagnosis is often delayed. This report highlights the need for a big suspicious index of the disease for an accurate and early diagnosis.
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