{"title":"应用于植入式人工肾的PDMS和PES膜微过滤器","authors":"Y. Gu, N. Miki","doi":"10.1109/NEMS.2007.352138","DOIUrl":null,"url":null,"abstract":"We present a novel microfilter used for solutes separation by diffusion. The microfilter is composed of two micro chambers made of PDMS and one layer of porous membrane formed by wet phase immersion method using PES (polyethersulfone). A theoretical equation for the description of the diffusion in the microfilter was derived and verified to be capable of predicting concentration distributions. Filtering capacity for molecules with various molecule sizes of this microfilter was evaluated using solution samples of sodium chloride (NaCl) and FITC (Fluorescein Isothiocyanate) Dextrans (MW 4k, 20k, 70k and 250k). This microfilter can be applied to artificial kidneys which can be implanted in human bodies.","PeriodicalId":364039,"journal":{"name":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2007-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Microfilter Fabricated with PDMS and PES Membrane Applicable for Implantable Artificial Kidney\",\"authors\":\"Y. Gu, N. Miki\",\"doi\":\"10.1109/NEMS.2007.352138\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present a novel microfilter used for solutes separation by diffusion. The microfilter is composed of two micro chambers made of PDMS and one layer of porous membrane formed by wet phase immersion method using PES (polyethersulfone). A theoretical equation for the description of the diffusion in the microfilter was derived and verified to be capable of predicting concentration distributions. Filtering capacity for molecules with various molecule sizes of this microfilter was evaluated using solution samples of sodium chloride (NaCl) and FITC (Fluorescein Isothiocyanate) Dextrans (MW 4k, 20k, 70k and 250k). This microfilter can be applied to artificial kidneys which can be implanted in human bodies.\",\"PeriodicalId\":364039,\"journal\":{\"name\":\"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems\",\"volume\":\"35 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-04-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NEMS.2007.352138\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NEMS.2007.352138","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Microfilter Fabricated with PDMS and PES Membrane Applicable for Implantable Artificial Kidney
We present a novel microfilter used for solutes separation by diffusion. The microfilter is composed of two micro chambers made of PDMS and one layer of porous membrane formed by wet phase immersion method using PES (polyethersulfone). A theoretical equation for the description of the diffusion in the microfilter was derived and verified to be capable of predicting concentration distributions. Filtering capacity for molecules with various molecule sizes of this microfilter was evaluated using solution samples of sodium chloride (NaCl) and FITC (Fluorescein Isothiocyanate) Dextrans (MW 4k, 20k, 70k and 250k). This microfilter can be applied to artificial kidneys which can be implanted in human bodies.
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