维生素d与衰老:多种机制的相互作用

M. Goyal, Arun Kumar Kedia
{"title":"维生素d与衰老:多种机制的相互作用","authors":"M. Goyal, Arun Kumar Kedia","doi":"10.56543/aaeeu.2022.1.1.08","DOIUrl":null,"url":null,"abstract":"Vitamin D has anti-inflammatory and pro-autophagy actions and influences the genetic and epigenetic landscape to promote healthy aging. A deficiency of this vitamin leads to accelerated aging. Deficiency of vitamin D causes sarcopenia, osteoporosis, frailty and a high risk of fractures and consequently high morbidity. To complicate matters, in the elderly, various factors like reduced dietary intake, reduced mobility and sun exposure, decreased production and activation of vitamin D, reduction in the population of vitamin D receptors and diminished responsiveness of tissues to vitamin D cause reduced vitamin D levels and function. The above factors indicate that a special considered approach be adopted for the prevention and treatment of vitamin D deficiency in the elderly.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"VITAMIN D AND AGING: AN INTERPLAY OF MULTIPLE MECHANISMS\",\"authors\":\"M. Goyal, Arun Kumar Kedia\",\"doi\":\"10.56543/aaeeu.2022.1.1.08\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Vitamin D has anti-inflammatory and pro-autophagy actions and influences the genetic and epigenetic landscape to promote healthy aging. A deficiency of this vitamin leads to accelerated aging. Deficiency of vitamin D causes sarcopenia, osteoporosis, frailty and a high risk of fractures and consequently high morbidity. To complicate matters, in the elderly, various factors like reduced dietary intake, reduced mobility and sun exposure, decreased production and activation of vitamin D, reduction in the population of vitamin D receptors and diminished responsiveness of tissues to vitamin D cause reduced vitamin D levels and function. The above factors indicate that a special considered approach be adopted for the prevention and treatment of vitamin D deficiency in the elderly.\",\"PeriodicalId\":437966,\"journal\":{\"name\":\"Anti-Aging Eastern Europe\",\"volume\":\"13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anti-Aging Eastern Europe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.56543/aaeeu.2022.1.1.08\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anti-Aging Eastern Europe","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56543/aaeeu.2022.1.1.08","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

维生素D具有抗炎和促自噬作用,影响遗传和表观遗传景观,促进健康衰老。缺乏这种维生素会加速衰老。缺乏维生素D会导致肌肉减少症、骨质疏松症、虚弱和骨折的高风险,从而导致高发病率。更复杂的是,在老年人中,各种因素,如减少饮食摄入量,减少流动性和阳光照射,维生素D的产生和激活减少,维生素D受体数量减少,组织对维生素D的反应性降低,导致维生素D水平和功能下降。上述因素表明,预防和治疗老年人维生素D缺乏症需要采取一种特殊的考虑方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
VITAMIN D AND AGING: AN INTERPLAY OF MULTIPLE MECHANISMS
Vitamin D has anti-inflammatory and pro-autophagy actions and influences the genetic and epigenetic landscape to promote healthy aging. A deficiency of this vitamin leads to accelerated aging. Deficiency of vitamin D causes sarcopenia, osteoporosis, frailty and a high risk of fractures and consequently high morbidity. To complicate matters, in the elderly, various factors like reduced dietary intake, reduced mobility and sun exposure, decreased production and activation of vitamin D, reduction in the population of vitamin D receptors and diminished responsiveness of tissues to vitamin D cause reduced vitamin D levels and function. The above factors indicate that a special considered approach be adopted for the prevention and treatment of vitamin D deficiency in the elderly.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
PROPER MEDICAL WRITING FOR TARGETING GLOBALLY VISIBLE JOURNALS AVASCULAR NECROSIS OF THE FEMORAL HEAD AFTER COVID-19: A CASE REPORT DIGITAL DETOX: A HOLISTIC APPROACH TO MENTAL AND PHYSICAL WELL-BEING WITH ANTI-AGING BENEFITS THE SECRETS OF HEALTHY AGING IN MEN: A MULTIDISCIPLINARY APPROACH BEYOND BOUNDARIES: THE LEGACY OF DMYTRO ZERBINO
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1