重症COVID-19患者血气分析特征与预后的关系

Helena Sembai, S. Wibawa, I. Handayani, Darmawaty E Rauf
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引用次数: 0

摘要

冠状病毒通常会感染呼吸道,导致严重的肺炎。在2019冠状病毒病(COVID-19)患者中,呼吸问题会导致多种酸碱失调。几项研究探索了在本次大流行期间用于COVID-19患者管理和预后的实验室生物标志物;然而,只有少数人关注血气分析。确定重症监护病房(ICU)重症COVID-19患者血气分析模式及其与预后的关系。这项回顾性队列研究使用了2021年1月至12月期间在Hasanuddin大学医院ICU接受治疗的重症COVID-19患者的次要数据。男性(58.8%)高于女性(41.5%),平均年龄62岁。呼吸性碱中毒是最常见的血气疾病(24.4%)。代谢性碱中毒是一种血气疾病,恢复/改善结果最多(8例)。血气分析结果与重症COVID-19转归无显著相关性。此外,在血气分析结果中没有发现特定的模式。呼吸性碱中毒是这些患者最常见的血气疾病。
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The Relationship between Blood Gas Analysis Profile and the Outcome of Severe COVID-19 Patients
Coronaviruses commonly infect the respiratory tract, leading to severe pneumonia. Respiratory problems cause numerous acid-base disorders in 2019 Coronavirus Disease (COVID-19) patients. Several studies have explored laboratory biomarkers used in the management and prognosis of COVID-19 patients during this pandemic; however, only a few focused on blood gas analysis. Determine the blood gas analysis pattern and its association with the outcome of severe COVID-19 patients treated in the Intensive Care Unit (ICU). This retrospective cohort study used secondary data from patients with severe COVID-19 treated in the ICU of Hasanuddin University Hospital between January and December 2021. There was a higher number of male (58.8%) compared to female patients (41.5%), with a mean age of 62 years. Respiratory alkalosis was the most prevalent blood gas disorder (24.4%). Metabolic alkalosis was a blood gas disorder with the highest number of recovery/improvement outcomes (8 patients). There was no significant relationship between blood gas analysis results and the outcome of severe COVID-19. In addition, no specific pattern was found in the results of blood gas analysis. Respiratory alkalosis was the most frequent blood gas disorder detected in these patients.
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