基于关联开放数据的临床文献风险因素提取

S. Boytcheva, G. Angelova, Zhivko Angelov
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引用次数: 0

摘要

本文介绍了基于关联开放数据(LOD)增强的临床文本的风险因素分析实验。这个想法是通过分析病人的门诊记录来确定病人是否有特定疾病的危险因素。构建了一个关于感兴趣疾病的“元知识”语义图,其中集成了来自Wikidata、PubMed、Wikipedia和MESH的症状、风险因素等多语言术语(标签),并通过ICD-10代码与个体患者的临床记录相关联。然后训练一个预测模型来预测患者是否有患感兴趣的疾病的风险。测试使用了2011-2016年期间全国存储库中的门诊记录。结果表明,当临床文本中添加LOD资源时,所有测试算法(kNN,朴素贝叶斯,树,逻辑回归,ANN)的整体性能都有所提高。
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Risk Factors Extraction from Clinical Texts based on Linked Open Data
This paper presents experiments in risk factors analysis based on clinical texts enhanced with Linked Open Data (LOD). The idea is to determine whether a patient has risk factors for a specific disease analyzing only his/her outpatient records. A semantic graph of “meta-knowledge” about a disease of interest is constructed, with integrated multilingual terms (labels) of symptoms, risk factors etc. coming from Wikidata, PubMed, Wikipedia and MESH, and linked to clinical records of individual patients via ICD–10 codes. Then a predictive model is trained to foretell whether patients are at risk to develop the disease of interest. The testing was done using outpatient records from a nation-wide repository available for the period 2011-2016. The results show improvement of the overall performance of all tested algorithms (kNN, Naive Bayes, Tree, Logistic regression, ANN), when the clinical texts are enriched with LOD resources.
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