基于经验模态分解和逻辑回归的肌电信号分类评估神经肌肉疾病

Muhammad Umar Khan, Sumair Aziz, M. Bilal, Muhammad Bilal Aamir
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引用次数: 40

摘要

肌电图(EMG)信号在肌肉纤维中产生,为神经肌肉疾病特别是肌萎缩性侧索硬化症(ALS)的评估提供了大量的信息,近年来已成为大量研究的主题。除此之外,设计一个准确且计算效率高的诊断系统仍然是一个挑战,因为不同肌肉在不同针头插入水平下的肌电图信号是不同的。该研究为肌电信号的准确分类提供了一个完整的框架,包括经验模态分解(EMD)去噪、时域和频域特征提取以及逻辑回归(LR)和支持向量机(SVM)分类。该方法能够有效地区分健康人与肌萎缩侧索硬化症患者的肌电信号,而不依赖于肌电信号采集的肌肉和针的插入水平。使用灵敏度、特异性、f值、总分类精度和ROC曲线下面积(AVC)等性能评价指标来验证两种分类器的性能。LR分类技术表现出最好的分类性能,分类准确率达到95.1%。结果表明所提出的诊断系统对肌电信号进行分类的能力。此外,该方法可用于神经肌肉疾病的临床诊断。
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Classification of EMG Signals for Assessment of Neuromuscular Disorder using Empirical Mode Decomposition and Logistic Regression
The electromyographic (EMG) signal generated in muscle fibers has been the topic under substantial research in immediate past years as it provides fairly large amount of information for assessment of neuromuscular diseases particularly amyotrophic lateral sclerosis (ALS). Besides this, the design of an accurate and computationally efficient diagnostic system remains a challenge due to variation of EMG signals taken from different muscles with different level of needle insertion. This study offers a complete framework for accurate classification of EMG signals which includes denoising by empirical mode decomposition (EMD), feature extraction from both the time and frequency domains and classification by logistic regression (LR) and support vector machine (SVM). The presented work efficiently discriminates between EMG signal of healthy subject and patient with ALS disease independent of which muscle is used for EMG signal acquisition and what insertion level of needle is. Performance evaluation measures such as sensitivity, specificity, F-measure, total classification accuracy and area under ROC curve (AVC) are used to validate the performance of both classifiers. LR classification technique shows superlative performance with a classification accuracy of 95.1%. These results shows the competence of proposed diagnostic system for classification of EMG signals. Moreover, the proposed method can be used in clinical applications for diagnoses of neuromuscular diseases.
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