医务人员暴露于电离辐射引起的癌症

X. Bacinschi
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摘要

电离辐射被列为一类致癌物。暴露于这种因素会增加患癌症的风险,研究人员的目标是建立暴露与风险水平之间的关系,以及限制暴露于这种因素的指导方针。这些风险是通过对原子弹幸存者、为诊断或治疗而暴露于辐射的人群以及专业暴露于辐射的人群——放射科医生、放射治疗师、铀矿工人、核工业操作人员——的研究来评估的。日本原子弹幸存者是最大的受辐射人群,研究年龄范围极广(从子宫内的辐照到老年人)。这一人口由93,000人组成,是用于确定低剂量辐射照射潜在风险的主要信息来源。自19世纪90年代以来,人们一直在研究从事电离辐射工作的卫生专业人员。在实施辐射防护系统后,随着技术的发展及其在各种专业领域的广泛使用,所接受的剂量有所下降,但又再次增加。最近进行的两项大规模长期研究提供了电离辐射职业照射所造成的癌症风险的信息,并阐明了监测受照射工作人员和重新评估辐射安全标准的必要性。这篇综述的重点是最近的文献有关辐射照射的医疗专业人员。
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Cancer induced by exposure to ionizing radiations in medical personnel
Abstract Ionizing radiation are classified as Class I carcinogens. The exposure to this factor increases the risk of developing cancer, and researchers aim to establish the relationship between the exposure and the risk levels, as well as guidelines which would limit exposure to it. The risks were assessed through studies related to the atomic bomb survivors, to the populations exposed to radiation for the purpose of diagnosis or therapy and to the professionally exposed populations – radiologists, radiotherapists, workers in uranium mines, operatives in the nuclear industry. The population of Japanese survivors of the atomic bombs is the largest population exposed and studied with an extremely wide age range (from the irradiation in utero to old people). This population, made up of 93.000 people, represents a major source of information used to determine the potential risk of low dose radiation exposure. Health professionals working with ionizing radiation have been studied ever since the 1890’s. After the implementation of a radiation protection system, the doses received decreased only to increase again with the technical development and its use in a wide variety of specialties. Two recent studies on large cohorts and during long periods of time brought information about the cancer risk due to occupational exposure to ionizing radiation and shed light on the need to monitor exposed staff and re-evaluate radiological safety standards. This review is focused on recent literature concerning the radiation exposure of medical professionals.
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