Yellow Fever

This chapter examines the history of yellow fever, the role it played in shaping slavery in the United States, and its part in the country’s westward expansion. Yellow fever was an endemic disease of West Africa that traveled to the New World and elsewhere aboard trading ships with their cargoes of slaves. The black African peoples, although easily infected, nevertheless withstood the effects in that fewer died from the infection than Caucasians, American Indians, or Asians. Ironically, as smallpox and measles devastated natives along the Caribbean coast and islands, growing numbers of African slaves were brought to replace those plantation laborers. When the value of Africans over natives became apparent, by virtue of the blacks’ resistance to yellow fever, the importation of these Africans increased still further. Because it was so lethal to susceptible humans, yellow fever actually disrupted exploration into the Caribbean. In fact, American expansion became possible only after a team led by Walter Reed arrived in Cuba to combat the disease and prove it was transmitted by the Aedes aegypti mosquito.