两种不同组织学的同步肿瘤-晚期宫颈腺癌伴交界性卵巢黏液性肿瘤一例22岁处女。

N. Kavitha, Tham Seng Who, Sachchithanantham Kanagasabai, Faizah Ahmad
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摘要

我们报告一例伴有交界性卵巢黏液性肿瘤的同步宫颈腺癌,患者为22岁处女,表现为持续出血和痛经4个月。经腹部超声显示子宫内膜腔内有液体。MRI显示子宫内膜腔扩张伴宫颈狭窄。抽液时发现有血肿,抽液后子宫腔空。她出院,随后在三个月时出现急性尿潴留和大出血。盆腔CT显示复杂的双侧卵巢囊肿伴少量腹水,L2主动脉旁淋巴结肿大,伴有宫颈狭窄的积血。探查性剖腹手术,膀胱切除术,结肠上网膜切除术,子宫和宫颈活检。病理表现为双侧卵巢交界性黏液瘤伴转移性大网膜结节及原发性宫颈高分化腺癌。胸部CT示转移性肺结节。鉴于晚期宫颈腺癌,建议姑息性化疗联合卡铂和紫杉醇6个周期。她目前已经完成了一个周期的化疗。结论:本病例为罕见的宫颈腺癌与双侧交界性卵巢肿瘤同时发生的不同组织学肿瘤之一,临床表现不典型,进展迅速。
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A Case Of Two Synchronous Tumour Of Different Histology - Advanced Cervical Adenocarcinoma With Borderline Mucinous Ovarian Tumour In A 22 Year Old Virgin.
We report a case of synchronous cervical adenocarcinoma with borderline mucinous ovarian tumourin a 22 year old virgin who presented with prolonged bleeding and dysmenorrhoea of four months duration. A transabdominal ultrasound demonstrated fluid in the endometrial cavity. This was confirmed by MRI pelvisrevealing adistended endometrial cavity with cervical stenosis. Evacuation revealed hematometra and the post evacuation uterine cavity is empty. She was discharged and subsequently presented at three months with acute urinary retention and heavy bleeding. A CT pelvisshowed complex bilateral ovarian cyst with minimal ascites, an enlarged paraaortic node at L2 and hematometrawith cervical stenosis. An exploratory laparotomy was performed with cystectomy, supracolicomentectomy with uterine and cervical biopsy. The histopathology shows bilateral borderline mucinous tumor of the ovary with metastatic omental nodules and primary well differentiated adenocarcinoma of the cervix. The subsequent CT thorax revealed metastatic pulmonary nodules. In view of advanced cervical adenocarcinoma, she was advised palliative chemotherapy with carboplatin and paclitaxel for six cycles. She has currently completed one cycle of chemotherapy. Conclusion:This case is one of the rare presentations of synchronous tumours of different histology with primary cervical adenocarcinoma and bilateral borderline ovarian tumour occurring in a virgin with atypical clinical presentation and rapid progression.
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