基于多孔硅和微针贴片的光控给药系统

P. Dardano, I. Rea, L. de Stefano, A. Caliò, J. Politi
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引用次数: 0

摘要

微针作为诊断和治疗的工具在生物医学中得到了广泛的应用。事实上,微针是皮肤和设备之间完美的无痛接口。以微针为界面,多孔硅膜为储液器和光控制器,实现智能给药装置成为可能。在本文中,我们提出了一个装载荧光素分子的贴片装置的制造和结果,作为概念的证明。
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Optically Controlled Drug Delivery System based on Porous Silicon and Microneedles patch
Microneedles have been widely applied in biomedicine as tool both in diagnostics and therapeutics. In fact, microneedles are the perfect and painless interface between the derma and a device. Using microneedles as interface and a porous Silicon membrane as reservoir and optical controller, it is possible to realize a smart device for drug delivery. In this paper, we present the fabrication and the results for a patch device loaded with fluorescein molecules, as proof of concept.
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