植物介导氧化锌纳米颗粒的合成及其抗微生物和抗氧化活性的评价

Prashast Kumar Tripathi Satish Chandra Sati
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摘要

摘要/ abstract摘要:本文首次报道了利用喜马拉雅药用植物黄花蒿叶提取物单锅法制备氧化锌纳米颗粒(ZnONPs)。最大限度地利用绿色化学原理,使合成不仅符合环境,而且具有成本效益。通过粉末XRD、HR-TEM、HR-SEM和FT-IR等仪器技术证实,所制得的纳米颗粒具有良好的形状和尺寸。合成的纳米颗粒的平均尺寸在26 ~ 35 nm之间。这些纳米颗粒随后被筛选用于抗微生物试验,在试验中显示出对大肠杆菌、A. Tereus和C. falcatum的阳性活性。合成的纳米颗粒的第二个应用是对DPPH抗氧化活性的估计。在乙醚中形成纳米颗粒的IC值为50 53,而标准抗坏血酸在相同溶剂中形成的IC值为26。关键词:刺梨,菊科,ZnONPs,抗菌活性和抗氧化活性
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Plant Mediated Synthesis of Zinc Oxide Nanoparticles and Evaluation of Its Anti - microbial and Anti - oxidant Activities
Abstract-In this research paper we have reported the single pot synthesis of zinc oxide nanoparticles (ZnONPs) for the first time by utilisation of leaves extract of Himalayan medicinal plant Artemisia roxburghiana. The principle of green chemistry was utilised at maximum possible level to make the synthesis not only environmentally compatible but also cost effective. The obtained nanoparticles are of good shape and size as confirmed by the instrumental techniques such as Powder XRD, HR-TEM, HR-SEM and FT-IR. The average size of the synthesized nanoparticles was between 26 to 35 nm. These nanoparticles then screened for the anti - microbial assay in which it has shown positive activity against E. coli, A. Tereus and C. falcatum. The second application of the synthesized nanoparticles is estimation of anti - oxidant activity against the DPPH. The IC value of the nanoparticles is formed to be 50 53 in EtoH while that of the standard, ascorbic acid was 26 in the same solvent. Keywords:Art emisia roxburghiana, Asteraceae, ZnONPs, Antimicrobial activity and Antioxidant activity
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